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Džubák Petr M.D., Ph.D.

Journals

Pooling of samples to optimise SARS-CoV-2 detection in nasopharyngeal swabs and gargle lavage self-samples for covid-19 diagnostics and surveillance. Infectious Diseases. 2024, 1-12, ISSN: 2374-4243, PMID: 38549542.
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action. European Journal of Medicinal Chemistry. 2024, 269, 116336, ISSN: 0223-5234, PMID: 38520761,  PDF.
Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties. Journal of Natural products. 2024, ISSN: 0163-3864, PMID: 38482846,

Books & book chapters

Detection and quantification of cellular antigens using flow cytometry, 1.vyd., Olomouc, Palacky University, 2021, 28, 209-214, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Laboratory Techniques in Cellular and Molecular Medicine, 1.vyd., Olomouc, Palacky University, 2021, 436 s, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Hmotnostní spektrometrie, 1. vyd, korigovaný dotisk, Olomouc, Univerzita Palackého v Olomouci, 2021, 2.2, 34-42, ISBN: 978-80-244-3951-8,

Intellectual property

RNA ISOLATION KIT (Džubák)

Utility Model: CZ 35067. Granted: 18.5.2021. Ownership: Palacký University Olomouc. Inventors: DŽUBÁK Petr, HAJDÚCH Marián, GURSKÁ Soňa, KOUDELÁKOVÁ Vladimíra, JAWOREK Hana.

Status: Available

METHOD OF IDENTIFICATION OF ENTITIES FROM MASS SPECTRA (Hruška)
  1. Published Application EP 18184710.4 under EP 3598135 (22.1.2020)
  2. Published Application PCT/EP2019/069552 under WO 2020/016428 (23.1.2020)
  3. Patent: JP 7218019. Granted: 27.1.2023. Ownership: Palacký University Olomouc. Inventors: HRUŠKA Miroslav, HAJDÚCH Marián, DŽUBÁK Petr

Status: Available

PYRIDINOPYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Veselovská)
  1. Patent: CZ 308104. Granted: 27. 11. 2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH MariánDŽUBÁK Petr
  2. Published Application PCT/CZ2019/050008 under WO 2019/174657 (19.9.2019)
  3. Patent: EP 3765475. Granted: 15.9.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH MariánDŽUBÁK Petr
  4. Patent: US 11,299,510. Granted: 12.4.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH MariánDŽUBÁK Petr
  5. Patent: CA 3.090.343. Granted: 4.10.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH MariánDŽUBÁK Petr
  6. Patent: JP 6973761. Granted: 8.11.202. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH MariánDŽUBÁK Petr
  7. Patent: AU 2019235042. Granted: 17.6.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH MariánDŽUBÁK Petr

Status: Available

Postdoctoral mentorship

Znojek Pawel Ph.D.

HCT/HCA assays development

Status: Ongoing from 2013 to 2015.

Doctoral mentorship

Ječmeňová Kateřina

Drug resistance mechanisms in cancer

Status: Ongoing from 2020.
Kotulová Jana Ph.D.

Identification of adenosine receptor modulators and their anticancer properties

Status: Graduated from 2014 to 2022.
Stanková Jarmila

Cytotoxic drugs molecular target identification by methods of cell biology and proteomics

Status: Ongoing from 2016 to 2024.

Master mentorship

Ječmeňová Kateřina

Development and characterization of resistant cell lines to purine and pyrimidine cytotoxic drugs

Status: Graduated from 2018 to 2020.
Růžičková Eliška B.Sc.

Evaluation of biological activity of demethylation drugs

Status: Graduated from 2013 to 2014.
Pastorková Barbora B.Sc.

Identification of molecular targets of anticancer drugs by immuno-affinity purification

Status: Graduated from 2013 to 2014.

Bachelor mentorship

Lónová Kateřina

Development and basic characterization of the cell line resistant to the CDK inhibitors

Status: Graduated from 2015 to 2016.

Open positions

Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training