Scientist and pediatrician involved in molecular and translational medicine (disease area oncology and infectious diseases), leader of research program Chemical Biology and Experimental Therapeutics at IMTM. Actively participated in the research of more than 20 national and international projects; member of advisory board of Cancer Research Foundation „Rakovina ve veřejná“, co-founder of spin-off company focused on manufacturing of molecular diagnostics. Published more than >100 papers and books/chapters, >1850 SCI citations, H-index 20, Prix de Pharmacie 2007 Ambassade de France – Sanofi-aventis, Premier Prix.
Specialties: Molecular and translational medicine, Oncology, Drug research and development, MOA, epigenetics, drug resistance
Responsible for financial and administrative management of the Institute with annual operation budget about CZK 200 mil.
Preparation of agreements/contracts and other legal documents for institute´s purposes, preparation of internal rules and its modifications, monitoring of compliance with general binding legal regulations, preparation of tender documentation according to the law on public contracts; realization, coordination and supervision on tender processes (public procurement).
Linda graduated in law at the Charles University, Prague, in 2002. Linda specializes in Intellectual Property Rights in academia. She is in charge of comprehensive care of research outputs, including legal protection and technology transfer. Linda has extensive experience in tech transfer of research outputs in the field of chemistry, organic technology, biochemistry and biomedicine. As a lawyer she focuses on IP law, license agreements, contractual or collaborative research in academia, including EU funded projects. Linda is a lecturer of IP Law, she provides lectures for academia and other research institutions and companies.
My interests concern applied genetics. Application ranges from clinical diagnostics of inherited diseases and detection of somatic mutations in tumor to forensic identification and kinship testing. I insist on regulated quality and prefer Bayesian interpretation.
Dr. Hlaváč is organic chemist focused on development of new compounds of various types. He is working in area of organic, bioorganic and medicinal chemistry. His interest covers synthesis of new anticancer drugs and novel diagnostic tools. Besides that, he studies new organic reactions applicable in organic synthesis in solution as well as in solid support. He is principle investigator of several grant projects including also international participation, several Czech and international patents. His results are presented in more than 60 articles in impacted journals, several lectures in international conferences and universities abroad. Dr. Hlaváč works as head of department of organic chemistry in Faculty of Science, Palacký University and as leader of Medicinal Chemistry work package. He is member of Czech chemical society as well as American chemical society. SCI citation 390; H-index = 11
Scientist specialized on cellular DNA damage response and its link to cancer development and treatment. Other specialization is advanced microscopic techniques. Actively participated in the research of more than 6 national and international projects. Published more than >25 original investigations and 3 patents, >750 SCI citations, H-index 10
Providing of administrative operations on IMTM, personnel administration, administrative of R&D projects. Quality manager in IMTM laboratories according to ISO17025 and ISO15189.