Frydrych Ivo Ph.D.
Journals
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes.
European Journal of Medicinal Chemistry.
2022,
244,
114850,
ISSN: 0223-5234,
PMID: 36283179,
Books & book chapters
Reporters based on luminescence or fluorescence detection ,
1.vyd.,
Olomouc,
Palacky University,
2021,
20,
147-152,
Dedication: LO1304,
ISBN: 978-80-244-6049-9,
Cell cycle analysis by flow cytometry ,
1.vyd.,
Olomouc,
Palacky University,
2021,
26,
193-200,
Dedication: LO1304,
ISBN: 978-80-244-6049-9,
Intellectual property
METHOD OF PREDICTING THE TUMOR RESPONSE TO DNA METHYLATION INHIBITORS AND ALTERNATIVE THERAPEUTIC REGIMENS FOR OVERCOMING RESISTANCE (Khushboo)
- Patent appl. EP 14161897.5 (ASH1L); Patent: EP 2924125; Granted: 17.6.2017; Ownership: Palacky University Olomouc; Inventors: Agrawal Khushboo, Frydrych Ivo, Džubák Petr, Hajdúch Marián
- Patent appl. EP 16158309.1 (JQ1) [divisional]; Patent: EP 3042650; Granted: 14.5.2020; Ownership: Palacky University Olomouc; Inventors: Agrawal Khushboo, Frydrych Ivo, Džubák Petr, Hajdúch Marián
- Published Application PCT/CZ2015/000029 under WO 2015/144102 (1.10.2015)
- Patent appl. EP 15717786.6 (BRD4); Patent: EP 3122902; Granted: 16.5.2018; Ownership: Palacký University Olomouc; Inventors: Agrawal Khushboo, Frydrych Ivo, Džubák Petr, Hajdúch Marián
- Published Application US 15/128,390 under US 20180251847 (6.9.2018)
- Patent appl. JP 2016-559355 (BRD4); Patent: JP 6463372; Granted: 11.1.2019; Ownership: Palacký University Olomouc; Inventors: Agrawal Khushboo, Frydrych Ivo, Džubák Petr, Hajdúch Marián
Status: Available
TRITERPENES WITH INHIBITORY ACTIVITY ON THE HEDGEHOG SIGNALING PATHWAY FOR USE IN THE TREATMENT OF CANCER DISEASES (Urban)
- Priority Application: PV 2022-277. Filed: 21.6.2022. Inventors: URBAN Milan, FRYDRYCH Ivo, BORKOVÁ Lucie, VRÁNOVÁ Barbora, HAJDÚCH Marián. Ownership: Palacký University Olomouc.
Status: Patent pending; Available
Master mentorship
Reiterová Ivana
Preparation of cell-based reporter assay for high-throughput screening of small molecules as potential receptor for advanced glycation endproducts inhibitors
Status:
Graduated from 2015 to 2017.
Bachelor mentorship
Pitnerová Monika
Targeting Hedgehog signaling by betulinic acid derivatives
Status:
Ongoing from 2021.