Contakt

Znojek Pawel Ph.D.

Academic Title: Mgr
E-mail: pawel.znojek@upol.cz
Phone: +420 585632174
Curriculum Vitae: download here

Research Interests

  • Cell Cycle and DNA repair mechanism
  • Development and validation  of assay for HTS and HCA screening platforms
  • Analysis of microscopic images
  • Laboratory automatisation with robotic station

Publications (Impact Factor Journals)

  • [6]
    LOBAZ, V., R. KONEFAL, J. PANEK, M. VLK, J. KOZEMPEL, M. PETŘÍK, Z. NOVÝ, S. GURSKÁ, P. ZNOJEK, P. STEPANEK a M. HRUBY. In Situ In Vivo radiolabeling of polymer-coated hydroxyapatite nanoparticles to track their biodistribution in mice. Colloids and surfaces. B, Biointerfaces. 2019, 179, 143-152. ISSN 0927-7765. IF: 3.997. PMID: 30954015
  • [5]
    TOKARENKO, A., B. LIŠKOVÁ, S. SMOLEN, N. TÁBORSKÁ, M. TICHÝ, S. GURSKÁ, P. PERLÍKOVÁ, I. FRYDRYCH, E. TLOUŠŤOVÁ, P. ZNOJEK, H. MERTLIKOVA-KAISEROVA, L. POSTOVA SLAVETINSKA, R. POHL, B. KLEPETAROVA, N. KHALID, Y. WENREN, R. LAPOSA, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides. Journal of Medicinal Chemistry. 2018, 61(20), 9347-9359. ISSN 0022-2623. IF: 6.253. PMID: 30281308
  • [4]
    OŽDIAN, T., D. HOLUB, Z. MACEČKOVÁ, L. VARANASI, G. RYLOVÁ, J. ŘEHULKA, J. VÁCLAVKOVÁ, H. SLAVÍK, P. MOUDRÝ, P. ZNOJEK, J. STANKOVÁ, J.B. DE SANCTIS, M. HAJDÚCH a P. DŽUBÁK. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells. Journal of Proteomics. 2017, 162, 73-85. ISSN 1874-3919 . IF: 3.867. PMID: 28478306
  • [3]
    ŘEHULKA, J., N. ANNADURAI, I. FRYDRYCH, P. ZNOJEK, P. DŽUBÁK, P. NORTHCOTE, J.H. MILLER, M. HAJDÚCH a V. DAS. Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells. Biochimica et Biophysica Acta. 2017, 17, 30124-1. ISSN 0304-4165. IF: 5.083. PMID: 28366502
  • [2]
    PERLÍKOVÁ, P., G. RYLOVÁ, P. NAUŠ, T. ELBERT, E. TLOUŠŤOVÁ, A. BOURDERIOUX, L. SLAVĚTÍNSKÁ, K. MOTYKA, D. DOLEŽAL, P. ZNOJEK, A. NOVÁ, M. HARVANOVÁ, P. DŽUBÁK, M. ŠILLER, J. HLAVÁČ, M. HAJDÚCH a M. HOCEK. 7-(2-Thienyl)-7-deazaadenosine (AB61), a new potent nucleoside cytostatic with a complex mode of action. Molecular Cancer Therapeutics. 2016, 15(5), 922-937. ISSN 1535-7163 . IF: 5.764. PMID: 26819331
  • [1]
    FUNK, P., K. MOTYKA, P. DŽUBÁK, P. ZNOJEK, S. GURSKÁ, J. KUSZ, C. MCMASTER, M. HAJDÚCH a M. SOURAL. Preparation of 2-phenyl-3-hydroxyquinoline- 4(1H)-one-5-carboxamides as potential anticancer and fluorescence agents. RSC Advances. 2015, 5(60), 48861-48867. ISSN 2046-2069. IF: 3.289.
  • Publications (Other Reviewed Journals)

  • [1]
    KONEČNÝ, P., S. GURSKÁ, P. ZNOJEK, E. SCHADICH, M. HAJDÚCH a P. DŽUBÁK. Reprofilování jako úspěšná strategie hledání nových léčiv. Farmakologická léčba. 2015, 4(10/2015), 12-18. ISSN 1805-398X.


  • Bachelor students mentor:

    [1] Denisa Mikolajková, Development of high throughput screening assay for detection of E2F mediated signaling pathways,
    status: Graduated, from: 2013 to 2015