De Sanctis Juan Bautista Ph.D.

Akademický titul: Professor

E-mail: juanbautista.desanctis@upol.cz

Telefon: 776391255

Skupiny: IMTM, LEM, PERSONÁL

I was initially formed in Biochemistry (Temple University), and then I did doctoral studies in physiological sciences, specialising in Biochemistry, Metabolism and immunology. I was a professor for more than 30 years at the Faculty of Medicine and the Institute of Immunology of the Faculty of Medicine of Universidad Central de Venezuela. My big area of expertise is inflammation, with ample background in immune response, cell metabolism, lipidomic, signal transduction and pharmacology. Currently, I am involved in a project on Cancer and immune response and others in Covid and long Covid (pending funding).

RAMPEESA, N., R. GUNDLA, G. MUDASANI, S. TANGALLAPALLI, S. ANUGU, S. GURSKÁ, J. DE SANCTIS, P. DŽUBÁK, M. HAJDÚCH, V. DAS

Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity. Bioorganic Chemistry. 2025, 157, 108316, ISSN: 0045-2068, PMID: 40037026, PDF.

DUMUT, D., M. HAJDÚCH, A. ZACHARIAS, Q. DUAN, I. FRYDRYCH, Z. ROŽÁNKOVÁ, M. POPPER, D. GARIC, R. PAUN, A. CENTORAME, J. SHAH, M. MISTRÍK, P. DŽUBÁK, J. DE SANCTIS, D. RADZIOCH

Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis. Frontiers in Immunology. 2025, 16, 1491450, ISSN: 1664-3224 , PMID: 40013140, PDF.

GARMENDIA, J., C. DE SANTCTIS, M. HAJDÚCH, J. DE SANCTIS

Exploring the Immunological Aspects and Treatments of Recurrent Pregnancy Loss and Recurrent Implantation Failure. International Journal of Molecular Sciences. 2025, 26(3), 1295, ISSN: 1661-6596, PMID: 39941063, PDF.

1 Molecular and Translational Medicine

Projekt:	Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí:	De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici:	5
Určeno pro:	Doctoral training

1 Molekulární a translační medicína

Projekt:	Role of PD1 signaling in the immune response against solid tumors
Vedoucí:	De Sanctis Juan Bautista Ph.D.
K dispozici:	2
Určeno pro:	Doktorské studium
Souhrn:	1 místo (plný úvazek), 1 místo (částečný úvazek)

De Sanctis Juan Bautista Ph.D.

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