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Groups: IMTM, LEM, STAFF

Journals

CHANDGUDE, A., G. LORIGA, A. BECCU, F. IANNOTTI, E. PAGANO, R. CAPASSO, R. FUSCO, P. SPANU, F. ULGHERI, A. DÖMLING
Structure-based design of a 1H-Tetrazole-containing scaffold for Caspase-1 inhibition: Synthesis, biological evaluation, and preliminary in Vivo studies. Bioorganic & Medicinal Chemistry. 2026, 143, 118794, ISSN: 0968-0896, PMID: 42700635,  PDF.
MOREIRA PEREIRA, T., A. REYES ROMERO, M. VAN DER LAAN, Z. GUAN, R. OERLEMANS, M. GROVES, M. MORI, F. MENEGHETTI, A. DÖMLING
Structural and Biophysical Characterization of Aminobenzo[ d]isothiazole 1,1-Dioxide SOS1 Ligands. ACS Medicinal Chemistry Letters. 2026, 17(8), 1895-1900, ISSN: 1948-5875, PMID: 42621470,  PDF.
JAVID, M., A. DÖMLING, M. NIKKHAH, G. POPOWICZ, M. HASHEMABADI, A. SHAHVERDI, Z. SEPEHRIZADEH, A. EBRAHIM-HABIBI, S. HOSSEINKHANI
Geometry-dependent interfaces shape NLRP3 pyrin domain assembly. International journal of biological macromolecules. 2026, 375, 153422, ISSN: 0141-8130 , PMID: 42425344,  PDF.

Books & book chapters

Multicomponent Reactions in Automated Synthetic Chemistry, 1.vyd., Berlin, WILEY‐VCH GmbH, 2026, 11, ISBN: 9783527355617,

Postdoctoral mentorship

Reyes Romero Atilio Ph.D.

Accellerated Drug Discovery and Screening

Status: Ongoing.

Doctoral mentorship

Masineni Samantha

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.

Mukim Mayur Shashikan

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.

Salama Kaoud MSc.

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.

Open positions

8 Molecular and cellular biology
Project: New anti-inflammatory small molecules
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Microsynthesis of drug candidates in medicinal chemistry
Supervisors: Dömling Alexander PhD.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Innovative approaches to modifiers of protein interactions
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Discovery of new antibacterial substances
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Discovery of new antitumor substances
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative drugs for Parkinson's disease
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative medicinal chemistry
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
6 Chemical biology and experimental therapeutics
Project: Decoding the binding principles of small molecules to RNA
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Modification of biologically active molecules leading to their improvement pharmacological properties
Supervisors: Dömling Alexander PhD.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: New methods of targeted protein degradation
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Drug repurposing for the treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
1 Bioinformatics / Chemoinformatics
Project: New chemoinformatic approaches to fragment-based drug discovery
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
1 Molecular and Translational Medicine
Project: Development of drugs in the field of small molecules 2 places in full-time study
Supervisors: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study