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Dömling Alexander PhD.

Journals

Baxdrostat: A First-in-Class Aldosterone Synthase Inhibitor for Resistant Hypertension. ACS Pharmacology & Translational Science. 2026, 9(4), 764-770, ISSN: 2575-9108, PMID: 41988370,  PDF.
VAN DER STRAAT, R., R. OERLEMANS, Y. CONG, J. BOXMA, R. BULAI, C. RIO-BERGE, L. KOEKEMOER, T. ZARGANES-TZITZIKAS, M. GUAN, P. MARPLES, F. REGGIORI, M. GROVES, A. DÖMLING
Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro. ACS Medicinal Chemistry Letters. 2026, 17(4), 856-865, ISSN: 1948-5875, PMID: 41982734,  PDF.
VAN DER STRAAT, R., J. KALINOWSKA-TLUSCIK, K. KURPIEWSKA, A. DÖMLING
Systematic Expansion of an Ugi-Based Multicomponent Synthesis of Tetrasubstituted Imidazoles. ACS Omega. 2026, 11(13), 20889-20894, ISSN: 2470-1343, PMID: 41970876,  PDF.

Postdoctoral mentorship

Reyes Romero Atilio Ph.D.

Accellerated Drug Discovery and Screening

Stav: Probíhající.

Doctoral mentorship

Masineni Samantha

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Stav: Probíhající od 2024.
Mukim Mayur Shashikan

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Stav: Probíhající od 2024.
Salama Kaoud MSc.

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Stav: Probíhající od 2024.

Open positions

Projekt: New anti-inflammatory small molecules
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Microsynthesis of drug candidates in medicinal chemistry
Vedoucí: Dömling Alexander PhD.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Innovative approaches to modifiers of protein interactions
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Utilization of the space of unprecedented covalent inhibitors
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Discovery of new antibacterial substances
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Discovery of new antitumor substances
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Innovative drugs for Parkinson's disease
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Innovative medicinal chemistry
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Decoding the binding principles of small molecules to RNA
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Targeted approaches to covalent inhibitors
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Vedoucí: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Modification of biologically active molecules leading to their improvement pharmacological properties
Vedoucí: Dömling Alexander PhD.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: New methods of targeted protein degradation
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Drug repurposing for the treatment and prevention of diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: New chemoinformatic approaches to fragment-based drug discovery
Vedoucí: Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Development of drugs in the field of small molecules 2 places in full-time study
Vedoucí: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study