Stránská Jana Ph.D.

Academic title: Mgr.

Phone: +420 585632070

Groups: IMTM, LEM, POSTDOCTORAL FELLOW, STAFF

Biomarkers for prognostic and predictive purposes

I focus mainly on identification, verification, and implementation of biomarkers for prognostic and predictive purposes in colorectal, lung, thyroid cancer and melanoma with utilization of instrumental capacities of Institute of Molecular and Translational Medicine. These biomarkers can be applied in situations directly linked to patient care, drug development, and research. My ultimate goal is to strengthen the knowledge base in identification and validation of biomarkers on the molecular level.

Publications:

Lukas J, Drabek J, Dudesek B, Vazan P, Stranska J, Jancik S, Mackova M, Syrucek M, Lukas D, Duskova J, Dundr P, Hintnausova B, Jiskra J. Correlation among the BRAF gene mutation status, clinicopathological features of primary tumour, and lymph node metastasizing of papillary thyroid carcinoma. Exp Clin Endocrinol Diabetes. 2014 May;122(5):268-72. doi: 10.1055/s-0034-1372624. Epub 2014 May 16.

Kallifatidis B, Borovička J, Stránská J, Drábek J, Mills DK. Fluorescent Random Amplified Microsatellites (F-RAMS) analysis of mushrooms as a forensic investigative tool. Forensic Sci Int Genet. 2014 Mar;9:25-32. doi: 10.1016/j.fsigen.2013.10.009. Epub 2013 Nov 2.

Stránská J, Tylichová M, Kopecný D, Snégaroff J, Sebela M. Biochemical characterization of pea ornithine-delta-aminotransferase: substrate specificity and inhibition by di- and polyamines. Biochimie. 2010 Aug;92(8):940-8. doi: 10.1016/j.biochi.2010.03.026. Epub 2010 Apr 8.

Stránská J, Kopecný D, Tylichová M, Snégaroff J, Sebela M. Ornithine delta-aminotransferase: An enzyme implicated in salt tolerance in higher plants. Plant Signal Behav. 2008 Nov;3(11):929-35.

Stránská J, Sebela M, Tarkowski P, Rehulka P, Chmelík J, Popa I, Pec P. Inhibition of plant amine oxidases by a novel series of diamine derivatives. Biochimie. 2007 Jan;89(1):135-44. Epub 2006 Sep 11.

ŘEHULKOVÁ, A., J. CHUDÁČEK, A. PROKOPOVÁ, M. VIDLAŘOVÁ, J. STRÁNSKÁ, J. DRÁBEK, J. POTOČKOVÁ, R. TROJANEC, J. VRBKOVÁ, J. ŠKARDA, T. BOHANES, M. SZKORUPA, B. TOLMACI, J. KLEIN, J. SROVNAL, M. HAJDÚCH

Clinical and prognostic significance of detecting CEA, EGFR, LunX, c-met and EpCAM mRNA-positive cells in the peripheral blood, tumor-draining blood and bone marrow of non-small cell lung cancer patients. Translational Lung Cancer Research. 2023, 12(5), 1034-1050, ISSN: 2226-4477 , PMID: 37323172, PDF.

SLAVKOVSKÝ, R., J. STRÁNSKÁ, V. VĚNSKOVÁ, S. JANČÍK, L. KOTKOVÁ, P. VOJTA, P. FLODR, M. BARTOUŠKOVÁ, H. ŠTUDENTOVÁ, M. HAJDÚCH, J. DRÁBEK

Development and extensive analytical validation of deep amplicon sequencing for detecting KRAS and NRAS mutations in metastatic colorectal cancer samples. Neoplasma. 2021, 69(1), 203-2015, ISSN: 0028-2685, PMID: 34881628,

KLASKOVA, E., J. DRÁBEK, M. HOBZOVA, V. SMOLKA, M. SEDA, J. HYJÁNEK, R. SLAVKOVSKÝ, J. STRÁNSKÁ, M. PROCHAZKA

Significant phenotype variability of congenital central hypoventilation syndrome in a family with polyalanine expansion mutation of the PHOX2B gene. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(4), 495-498, ISSN: 1213-8118, PMID: 27485184,

DRÁBEK, J., A. JURCEKOVA, J. NOVACKOVA, J. STRÁNSKÁ, J. VRBKOVÁ, A. BARTAKOVA, L. KOTKOVÁ, M. DAJBYCHOVA, R. SLAVKOVSKÝ, T. PEXA, V. STENZL

Vybrané metody forenzní genetiky, 1.vyd., Olomouc, Palacky University, 2022, 1 s, ISBN: 978-80-244-6177-9,

STRÁNSKÁ, J.

STR profiling for cell line authentication , 1.vyd., Olomouc, Palacky University, 2021, 4, 29-36, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Stránská Jana Ph.D.

About me

Journals

Books & book chapters