Contakt

Stránská Jana Ph.D.

Academic Title: Mgr.
Phone: +420 585632070
Groups: Staff, LEM, Postdoctoral Fellow

Postdoctoral training

Biomarkers for prognostic and predictive purposes.

The project focuses mainly on identification, verification, and implementation of biomarkers for prognostic and predictive purposes in colorectal, lung, thyroid cancer and melanoma with utilization of instrumental capacities of Institute of Molecular and Translational Medicine. These biomarkers can be applied in situations directly linked to patient care, drug development, and research. The ultimate goal is to strengthen the knowledge base in identification and validation of biomarkers on the molecular level.

Status: Ongoing.

About me

Biomarkers for prognostic and predictive purposesI focus mainly on identification, verification, and implementation of biomarkers for prognostic and predictive purposes in colorectal, lung, thyroid cancer and melanoma with utilization of instrumental capacities of Institute of Molecular and Translational Medicine. These biomarkers can be applied in situations directly linked to patient care, drug development, and research. My ultimate goal is to strengthen the knowledge base in identification and validation of biomarkers on the molecular level. Publications:Lukas J, Drabek J, Dudesek B, Vazan P, Stranska J, Jancik S, Mackova M, Syrucek M, Lukas D, Duskova J, Dundr P, Hintnausova B, Jiskra J. Correlation among the BRAF gene mutation status, clinicopathological features of primary tumour, and lymph node metastasizing of papillary thyroid carcinoma. Exp Clin Endocrinol Diabetes. 2014 May;122(5):268-72. doi: 10.1055/s-0034-1372624. Epub 2014 May 16.Kallifatidis B, Borovička J, Stránská J, Drábek J, Mills DK. Fluorescent Random Amplified Microsatellites (F-RAMS) analysis of mushrooms as a forensic investigative tool. Forensic Sci Int Genet. 2014 Mar;9:25-32. doi: 10.1016/j.fsigen.2013.10.009. Epub 2013 Nov 2.Stránská J, Tylichová M, Kopecný D, Snégaroff J, Sebela M. Biochemical characterization of pea ornithine-delta-aminotransferase: substrate specificity and inhibition by di- and polyamines. Biochimie. 2010 Aug;92(8):940-8. doi: 10.1016/j.biochi.2010.03.026. Epub 2010 Apr 8.Stránská J, Kopecný D, Tylichová M, Snégaroff J, Sebela M. Ornithine delta-aminotransferase: An enzyme implicated in salt tolerance in higher plants. Plant Signal Behav. 2008 Nov;3(11):929-35.Stránská J, Sebela M, Tarkowski P, Rehulka P, Chmelík J, Popa I, Pec P. Inhibition of plant amine oxidases by a novel series of diamine derivatives. Biochimie. 2007 Jan;89(1):135-44. Epub 2006 Sep 11.
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