FANG, L., B. ZHU, Y. ZHAO, W. CHEN, Z. YANG, L. KERRIGAN, K. LANGEBACH, M. DE MARS, K. IDLER, H. JACOB, Y. ZHENG, Y. YU, E. JAEGER, G. SCHROTH, O. ABAAN, K. TALSANIA, J. LACK, T. SHEN, S. STANBOULY, B. TRAN, J. SHETTY, Y. KRIGA, D. MEERZAMAN, C. NGUYEN, V. PETITJEAN, M. SULTAN, M. CAM, M. MEHTA, T. HUNG, E. PETERS, R. KALAMEGHAM, S. SAHRAEIAN, M. MOHIYUDDI, T. GUO, L. YAO, L.A. SONG, H. LAM, J. DRÁBEK, P. VOJTA, R. MAESTRO, D. GASPAROTTO, S. KOKS, E. REIMANN, A. SCHERER, J. NORDLUND, U. LILJEDAHL, R. JENSEN, M. PIROOZNIA, Z. LI, C. XIAO, S. SHERRY, R. KUSKO, M. MOOS, E. DONALDSON, Z. TEZAK, B. NING, W. TONG, J. LI, P. DUERKEN-HUGHES, C. CATALANOTTI, S. MAHESHWARI, J. SHUGA, W. LIANG, J. KEATS, J. ADKINS, E. TASSONE, V. ZISMANN, T. MCDANIEL, J. TRENT, J. FOOX, D. BUTLER, C. MASON, H. HONG, C. WANG, W. XIAO a I. SOMATIC MUTATION WORKING GROUP OF SEQUENCING QUALITY CONTROL PHASE II CONSORTIUM.
Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing.
Nature Biotechnology.
2021,
39(9),
1151-60.
ISSN 1087-0156.
IF: 54.908.
PMID:
34504347
XIAO, W., L. FANG, Y. ZHAO, J. LACK, M. GUAN, B. ZHU, E. JAEGER, L. KERRIGAN, T. BLOMQUIST, T. HUNG, M. SULTAN, K. IDLER, A. SCHERER, R. KUSKO, M. MOOS, C. XIAO, S. SHERRY, O. ABAAN, W. CHEN, X. CHEN, J. NORDLUND, U. LILJEDAHL, R. MAESTRO, M. POLANO, J. DRÁBEK, P. VOJTA, S. KOKS, E. REIMANN, B. MADALA, T. MERCER, C. MILLER, H. JACOB, T. TRUONG, A. MOSHREFI, A. NATARAJAN, A. GRANAT, G. SCHROTH, R. KALAMEGHAM, E. PETERS, V. PETITJEAN, A. WALTON, T. SHEN, K. TALSANIA, C. VERA, K. LANGEBACH, M. DE MARS, J. HIPP, J. WILLEY, J. WANG, J. SHETTY, Y. KRIGA, A. RAZIUDDIN, B. TRAN, Y. ZHENG, Y. YU, M. CAM, P. JAILWALA, C. NGUYEN, D. MEERZAMAN, Q. CHEN, B. ERNEST, U. MEHRA, R. JENSEN, W. JONES, J. LI, B. PAPAS, M. PIROOZNIA, Y. CHEN, F. SEIFUDDIN, Z. LI, X. LIU, W. RESCH, J. WANG, L. WU, G. YAVAS, C. MILES, B. NING, W. TONG, C. MASON, E. DONALDSON, S. LABABIDI, L. STAUDT, Z. TEZAK, H. HONG a C. WANG.
Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing.
Nature Biotechnology.
2021,
39(9),
1141-50.
ISSN 1087-0156.
IF: 54.908.
PMID:
34504346
POKORNÝ, J., D. OLEJNÍKOVÁ, I. FRYDRYCH, B. LIŠKOVÁ, S. GURSKÁ, S. BENICKÁ, J. ŠAREK, J. KOTULOVÁ, M. HAJDÚCH, P. DŽUBÁK a M. URBAN.
Substituted dienes prepared from betulinic acid - Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters.
European Journal of Medicinal Chemistry.
2021,
224,
113706.
ISSN 0223-5234.
IF: 6.514.
PMID:
34311159
MISTRÍK, M., Z. ŠKROTT, P. MULLER, A. PANACEK, L. HOCHVALDOVA, K. CHROMÁ, T. BUCHTOVÁ, V. VANDOVA, L. KVÍTEK a J. BÁRTEK.
Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response.
Nature Communications.
2021,
12(1),
713.
ISSN 2041-1723.
IF: 12.121.
PMID:
33514738
GONZALES, G., J. HODOŇ, A. KAZAKOVA, C. D´ACUNTO, P. KANOVSKY, M. URBAN a M. STRNAD.
Novel pentacyclic triterpenes exhibiting strong neuroprotective activity in SH-SY5Y cells in salsolinol- and glutamate-induced neurodegeneration models.
European Journal of Medicinal Chemistry.
2021,
213,
113168.
ISSN 0223-5234.
IF: 5.573.
PMID:
33508480
VANDA, D., V. CANALE, S. CHAUMONT-DUBEL, R. KURCZAB, G. SATALA, K. P., M. KRAWCZYK, W. PIETRUS, K. BLICHARZ, E. PEKALA, A. BOJARSKI, P. POPIK, P. MARIN, M. SOURAL a P. ZAJDEL.
Imidazopyridine-Based 5-HT 6 Receptor Neutral Antagonists: Impact of N1-Benzyl and N1-Phenylsulfonyl Fragments on Different Receptor Conformational States.
Journal of Medicinal Chemistry.
2021,
64(2),
1180-1196.
ISSN 0022-2623.
IF: 6.205.
PMID:
33439019
POLISHCHUK, P.
CReM: chemically reasonable mutations framework for structure generation.
Journal of Cheminformatics.
2020,
12(1),
28.
ISSN 1758-2946.
IF: 5.326.
PMID:
33430959
URBAN, M., V. ŠLACHTOVÁ a L. BRULÍKOVÁ.
Small organic molecules targeting the energy metabolism of Mycobacterium tuberculosis.
European Journal of Medicinal Chemistry.
2021,
212,
113139.
ISSN 0223-5234 .
IF: 5.573.
PMID:
33422979
KRAJČOVIČOVÁ, S., R. JORDA, D. VANDA, M. SOURAL a V. KRYŠTOF.
1,4,6-Trisubstituted imidazo[4,5-c]pyridines as inhibitors of Bruton's tyrosine kinase.
European Journal of Medicinal Chemistry.
2020,
211,
113094.
ISSN 0223-5234.
IF: 5.573.
PMID:
33340912
SVEC, P., Z. NOVÝ, J. KUCKA, M. PETŘÍK, O. SEDLACEK, M. KUCHAR, B. LIŠKOVÁ, M. MEDVEDÍKOVÁ, K. KOLOUCHOVA, O. GROBORZ, L. LOUKOTOVA, R. KONEFAL, M. HAJDÚCH a M. HRUBY.
Iodinated Choline Transport-Targeted Tracers.
Journal of Medicinal Chemistry.
2020,
63(24),
15960–15978.
ISSN 0022-2623.
IF: 6.205.
PMID:
33271015
CHASÁK, J., V. ŠLACHTOVÁ, M. URBAN a L. BRULÍKOVÁ.
Squaric acid analogues in medicinal chemistry.
European Journal of Medicinal Chemistry.
2021,
209,
112872.
ISSN 0223-5234.
IF: 5.573.
PMID:
33035923
RUČILOVÁ, V., A. SWIERRCZEK, D. VANDA, P. FUNK, B. LEMROVÁ, A. GAWALSKA, A. BUCKI, B. NOWAK, M. ZADROZNA, K. POCIECHA, M. SOURAL, E. WYSKA, M. PAWLOWSKI, G. CHLON-RZEPA a P. ZAJDEL.
New imidazopyridines with phosphodiesterase 4 and 7 inhibitory activity and their efficacy in animal models of inflammatory and autoimmune diseases.
European Journal of Medicinal Chemistry.
2020,
209,
112854.
ISSN 0223-5234.
IF: 5.573.
PMID:
33022582
SVOBODOVA, L., M. DVORAKOVA, M. RUCKI, K. KEJLOVA, H. KANDAROVA, H. KOLÁŘOVÁ, M. MANNERSTROM a T. HEINONEN.
Safety testing of adult novelties using in vitro methods.
Regulatory Toxicology and Pharmacology.
2020,
117,
104780.
ISSN 0273-2300.
IF: 2.652.
PMID:
32898621
VERMISOGLOU, E., D. PANACEK, K. JAYARAMULU, M. PYKAL, I. FREBORT, M. KOLÁŘ, M. HAJDÚCH, R. ZBOŘIL a M. OTYEPKA.
Human virus detection with graphene-based materials.
Biosensors & Bioelectronics.
2020,
166,
112436.
ISSN 0956-5663.
IF: 10.257.
PMID:
32750677
PETŘÍK, M., E. UMLAUFOVÁ, V. RACLAVSKÝ, A. PALYZOVA, V. HAVLÍČEK, J. PFISTER, C. MAIR, Z. NOVÝ, M. POPPER, M. HAJDÚCH a C. DECRISTOFORO.
68 Ga-labelled desferrioxamine-B for bacterial infection imaging.
European Journal of Nuclear Medicine and Molecular Imaging.
2021,
48(2),
372-382.
ISSN 1619-7070.
IF: 7.081.
PMID:
32734456
JORDA, R., S. KRAJČOVIČOVÁ, P. KRÁLOVÁ, M. SOURAL a V. KRYŠTOF.
Scaffold hopping of the SYK inhibitor entospletinib leads to broader targeting of the BCR signalosome.
European Journal of Medicinal Chemistry.
2020,
204,
112636.
ISSN 0223-5234.
IF: 5.572.
PMID:
32731189
DVOŘANOVÁ ŠTĚPÁNKOVÁ, J., M. KUGLER, J. HOLUB, V. SICHA, V. DAS, J. NEKVINDA, S. EL ANWAR, M. HAVRANEK, K.. POSPISILOVA, M. FABRY, V. KRAL, M. MEDVEDÍKOVÁ, S. MATEJKOVA, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, J. BRYNDA, M. HAJDÚCH, B. GRUNER a P. ŘEZÁČOVÁ.
Sulfonamido Carboranes as Highly Selective Inhibitors of Cancer-Specific Carbonic Anhydrase IX.
European Journal of Medicinal Chemistry.
2020,
200,
112460.
ISSN 0223-5234.
IF: 5.572.
PMID:
32505851
KEJLOVA, K., H. BENDOVA, J. CHRZ, M. DVORAKOVA, L. SVOBODOVA, A. VLKOVA, L. KUBAC, R. KORINKOVA, J. CERNY, D. OCADLIKOVA, M. RUCKI, T. HEINONEN, D. JIROVA, S. LETASIOVA, H. KANDAROVA a H. KOLÁŘOVÁ.
Toxicological Testing of a Photoactive Phthalocyanine-Based Antimicrobial Substance.
Regulatory Toxicology and Pharmacology.
2020,
115,
104685.
ISSN 0273-2300 .
IF: 2.652.
PMID:
32454236
CHYRA, Z., T. SEVCIKOVA, P. VOJTA, J. PUTEROVA, L. BROZOVA, K. GROWKOVA, J. FILIPOVA, M. ZATOPKOVA, S. GROSICKI, A. BARCHNICKA, W. JEDRZEJCAK, A. WASCUK-GAJDA, A. JUNGOVA, A. MIKULASOVA, M. HAJDÚCH, M. MOKREJS, L. POUR, M. STORK, L. HARVANOVA, M. MISTRÍK, G. MIKALA, P. ROBAK, A. CZYZ, J. DEBSKI, L. USNARSKA-ZUBKIEWICZ, A. JURCZYSZYN, L. STEJSKAL, G. MORGAN, F. KRYUKOV, E. BUDINSKA, M. SIMICEK, T. JELINEK, M. HRDINKA a R. HAJEK.
Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis.
Haematologica.
2020,
106(2),
601-604.
ISSN 0390-6078.
IF: 7.570.
PMID:
32381580
FIEDLER, J., M. REISER, P. KOSTAL, J. KUBALE, S. OSTRY, T. HRBAC, P. KESNEROVA, T. FADRNA, K. LANGOVÁ, R. HERZIG a D. SKOLOUDIK.
Blood Flow Volume Measurement in Cervical and Intracranial Arteries using Quantitative Magnetic Resonance Angiography and Duplex Sonography (Bocaccia) - A Prospective Observational Study.
Ultraschall in der Medizin.
2020,
42(1),
65-74.
ISSN 0172-4614.
IF: 4.613.
PMID:
32340045
ŘEHULKA, J., K. BÜRGLOVÁ, P. KREJČÍ, S. GURSKÁ, P. HRADIL, M. HAJDÚCH, P. DŽUBÁK a J. HLAVÁČ.
Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors.
European Journal of Medicinal Chemistry.
2020,
192,
112176.
ISSN 0223-5234.
IF: 4.833.
PMID:
32120327
SAID, M., W. ELDEHNA, A. NOCENTINI, S. FAHIM, A. BONARDI, A. ELGAZAR, V. KRYŠTOF, D. SOLIMAN, H. ABDEL-AZIZ, P. GRATTERI, S. ABOU-SERI a C. SUPURAN.
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation.
European Journal of Medicinal Chemistry.
2020,
189(2020),
112019.
ISSN 0223-5234.
IF: 4.833.
PMID:
31972394
JORDA, R., P. MAGAR, D. HENDRYCHOVA, K. PAUK, M. DIBUS, E. PILAROVA, A. IMRAMOVSKY a V. KRYŠTOF.
Novel modified leucine and phenylalanine dipeptides modulate viability and attachment of cancer cells.
European Journal of Medicinal Chemistry.
2020,
188,
112036.
ISSN 0223-5234.
IF: 4.833.
PMID:
31931341
BORKOVÁ, L., I. FRYDRYCH, N. JAKUBCOVÁ, R. ADÁMEK, B. LIŠKOVÁ, S. GURSKÁ, M. MEDVEDÍKOVÁ, M. HAJDÚCH a M. URBAN.
Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid.
European Journal of Medicinal Chemistry.
2019,
185,
111806.
ISSN 0223-5234.
IF: 4.833.
PMID:
31677446
GRUNER, B., J. BRYNDA, V. DAS, V. SICHA, J. ŠTĚPÁNKOVÁ, J. NEKVINDA, J. HOLUB, K.. POSPISILOVA, M. FABRY, P. PACHL, V. KRAL, M. KUGLER, V. MAŠEK, M. MEDVEDÍKOVÁ, S. MATEJKOVA, A. NOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH a P. ŘEZÁČOVÁ.
Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX.
Journal of Medicinal Chemistry.
2019,
62(21),
9560-9575.
ISSN 0022-2623.
IF: 6.054.
PMID:
31568723
HODOŇ, J., L. BORKOVÁ, J. POKORNÝ, A. KAZAKOVA a M. URBAN.
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research.
European Journal of Medicinal Chemistry.
2019,
182,
111653.
ISSN 0223-5234.
IF: 4.833.
PMID:
31499360
VANZO, R., J. BARTKOVA, J. MERCHUT-MAYA, A. HALL., J. BOUCHAL, L. DYRSKJOT, L. FRANKEL, V.G. GORGOULIS, A. MAYA-MENDOZA, M. JAATTELA a J. BÁRTEK.
Autophagy role(s) in response to oncogenes and DNA replication stress.
Cell Death and Differentiation.
2019,
27(3),
1134-1153.
ISSN 1350-9047.
IF: 8.086.
PMID:
31409894
VOUGAS, K., T. SAKELAROPOULOS, A. KOTSINAS, G. FOUKAS, A. NTARGARAS, F. KOINIS, A. POLYZOS, V. MYRIANTHOPOULOS, H. ZHOU, S. NARANG, V. GEORGOULIAS, L. ALEXOPOULOS, I. AIFANTIS, P. TOWNSEND, P. SFIKAKIS, R. FITZGERALD, D. THANOS, J. BÁRTEK, R. PETTY, A. TSIRIGOS a V.G. GORGOULIS.
Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining.
Pharmacology & Therapeutics.
2019,
203,
107395.
ISSN 0163-7258.
IF: 9.396.
PMID:
31374225
LUPINO, L., T. PERRY, S. MARGIELEWSKA, R. HOLLOWS, M. IBRAHIM, M. CARE, J. ALLEGOOD, R. TOOZE, R. SABBADINI, G. REYNOLDS, R. BICKNELL, Z. RUDZKI, Y. LIN HOCK, U. ZANETTO, W. WEI, W. SIMMONS, S. SPIEGEL, C.B.J. WOODMAN, M. ROWE, K. VRZALIKOVA a P. MURRAY.
Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma.
Leukemia.
2019,
33(12),
2884-2897.
ISSN 0887-6924.
IF: 10.023.
PMID:
31097785
GARIC, D., J.B. DE SANCTIS, J. SHAH, D. DUMUT a D. RADZIOCH.
Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain.
Progress in Lipid Research.
2019,
74,
130-144.
ISSN 0163-7827.
IF: 8.435.
PMID:
30876862
BARTHELDYOVA, E., P. TURANEK KNOTIGOVA, K. ZACHOVÁ, J. MASEK, P. KULICH, R. EFFENBERG, D. ZYKA, F. HUBATKA, J. KOTOUCEK, H. CELECHOVSKA, R. HEZOVA, A. TOMECKOVA, E. MASKOVA, M. FOJTIKOVA, S. MACAULAY, P. BYSTRICKY, E. PAULOVICOVA, L. DROZ, M. LEDVINA, M. RAŠKA a J. TURANEK.
N-Oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: Synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells.
Carbohydrate Polymers.
2019,
207,
521-532.
ISSN 0144-8617.
IF: 5.158.
PMID:
30600036
DE LA FUENTE, G., F. TRALDI, J. ŠIROKÁ, A. KRETOWSKI, M. CIBOROWSKI, A. OTERO, C. BARBAS a J. GODZIEN.
Characterization and annotation of oxidized glycerophosphocholines for non-targeted metabolomics with LC-QTOF-MS data.
Analytica Chimica Acta.
2018,
1037,
358-369.
ISSN 0003-2670.
IF: 5.123.
PMID:
30292312
TOKARENKO, A., B. LIŠKOVÁ, S. SMOLEN, N. TÁBORSKÁ, M. TICHÝ, S. GURSKÁ, P. PERLÍKOVÁ, I. FRYDRYCH, E. TLOUŠŤOVÁ, P. ZNOJEK, H. MERTLIKOVA-KAISEROVA, L. POSTOVA SLAVETINSKA, R. POHL, B. KLEPETAROVA, N. KHALID, Y. WENREN, R. LAPOSA, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK.
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides.
Journal of Medicinal Chemistry.
2018,
61(20),
9347-9359.
ISSN 0022-2623.
IF: 6.253.
PMID:
30281308
KARLÍKOVÁ, R., J. ŠIROKÁ, M. MECH, D. FRIEDECKÝ, H. JANEČKOVÁ, L. MÁDROVÁ, F. HRDINOVA, Z. DRABKOVA, O. DOBESOVA, T. ADAM a P. JAHN.
Newborn foal with atypical myopathy.
Journal of Veterinary Internal Medicine.
2018,
32(5),
1768-1772.
ISSN 0891-6640.
IF: 2.185.
PMID:
30216546
BÜRGLOVÁ, K., G. RYLOVÁ, A. MARKOS, H. PŘICHYSTALOVÁ, M. SOURAL, M. PETRÁČEK, M. MEDVEDÍKOVÁ, G. TEJRAL, B. SOPKO, P. HRADIL, P. DŽUBÁK, M. HAJDÚCH a J. HLAVÁČ.
Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1 H)-quinolinones as Novel Ligands with Anticancer Activity.
Journal of Medicinal Chemistry.
2018,
61(7),
3027-3036.
ISSN 0022-2623.
IF: 6.259.
PMID:
29498519
AGRAWAL, K., V. DAS, P. VYAS a M. HAJDÚCH.
Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic.
Pharmacology & Therapeutics.
2018,
188,
45-79.
ISSN 0163-7258.
IF: 11.127.
PMID:
29454856
VANDA, D., M. SOURAL, V. CANALE, S. CHAUMONT-DUBEL, G. SATALA, T. KOS, P. FUNK, V. RUČILOVÁ, B. LEMROVÁ, K. P., E. PEKALA, A. BOJARSKI, P. POPIK, P. MARIN a P. ZAJDEL.
Novel non-sulfonamide 5-HT6 receptor partial inverse agonist in a group of imidazo[4,5-b]pyridines with cognition enhancing properties.
European Journal of Medicinal Chemistry.
2017,
144(2018),
716-729.
ISSN 0223-5234.
IF: 4.519.
PMID:
29291439
ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK.
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Nature.
2017,
552(7684),
194-199.
ISSN 0028-0836.
IF: 40.137.
PMID:
29211715
MODER, M., G. VELIMEZI, M. OWUSU, A. MAZOUZI, M. WIEDNER, J. FERREIRA DA SILVA, L. ROBINSON-GARCIA, F. SCHISCHLIK, R. SLAVKOVSKÝ, R. KRALOVICS, B. SCHUSTER, C. BOCK, T. IDEKER, S. JACKSON, J. MENCHE a J. LOIZOU.
Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.
Nature Communications.
2017,
8(1),
1238.
ISSN 2041-1723.
IF: 12.124.
PMID:
29089570
EIGNEROVA, B., M. TICHÝ, J. KRASULOVA, L. RAROVA, R. CHRISTOVÁ, M. URBAN, B. BEDNARCZYK-CWYNAR, M. HAJDÚCH a J. ŠAREK.
Q1_Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids.
European Journal of Medicinal Chemistry.
2017,
140,
403-420.
ISSN 0223-5234.
IF: 4.519.
PMID:
28987603
KARLÍKOVÁ, R., K. MIČOVÁ, L. NAJDEKR, A. GARDLO, T. ADAM, P. MAJEROVÁ, D. FRIEDECKÝ a A. KOVAC.
Metabolic status of CSF distinguishes rats with tauopathy from controls.
Alzheimer's Research & Therapy.
2017,
9(1),
78.
ISSN 1758-9193.
IF: 6.154.
PMID:
28934963
VRZALIKOVA, K., M. IBRAHIM, M. VOCKERODT, T. PERRY, S. MARGIELEWSKA, L. LUPINO, E. NAGY, E. SOILLEUX, D. LIEBELT, R. HOLLOWS, A. LAST, G. REYNOLDS, M. ABDULLAH, H. CURLEY, M. CARE, D. KRAPPMANN, R. TOOZE, J. ALLEGOOD, S. SPIEGEL, W. WEI, C.B.J. WOODMAN a P. MURRAY.
S1PR1 drives a feed forward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells.
Leukemia.
2018,
32(1),
214-223.
ISSN 0887-6924.
IF: 11.702.
PMID:
28878352
EFFENBERG, R., P. TURANEK KNOTIGOVA, D. ZYKA, H. CELECHOVSKA, J. MASEK, E. BARTHELDYOVA, F. HUBATKA, S. KOUDELKA, R. LUKAC, A. KOVALOVA, D. SAMAN, M. KŘUPKA, L. BARKOCZIOVA, P. KOSZTYU, M. ŠEBELA, L. DROZ, M. HUCKO, M. KANASKOVA, A.D. MILLER, M. RAŠKA, M. LEDVINA a J. TURANEK.
Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo.
Journal of Medicinal Chemistry.
2017,
60(18),
7745-7763.
ISSN 0022-2623.
IF: 6.259.
PMID:
28829599
NARDONE, G., J. OLIVER-DE LA CRUZ, J. VRBSKY, C. MARTINI, J. PRIBYL, P. SKLADAL, M. PESL, G. CALUORI, S. PAGLIARI, F. MARTINO, Z. MACEČKOVÁ, M. HAJDÚCH, A. SANZ-GARCIA, N. PUGNO, G. STOKIN a G. FORTE.
YAP regulates cell mechanics by controlling focal adhesion assembly.
Nature Communications.
2017,
15,
8:15321.
ISSN 2041-1723.
IF: 11.329.
PMID:
28504269
VAN GOOL, A., F. BIETRIX, E. CALDENHOVEN, K. ZATLOUKAL, A. SCHERER, J. LITTON, G. MEIJER, N. BLOMBERG, A. SMITH, B. MONS, J. HERINGA, W. KOOT, M. SMIT, M. HAJDÚCH, T. RIJNDERS a A.E. USSI.
Bridging the translational innovation gap through good biomarker practice.
Nature Reviews. Drug Discovery.
2017,
16(9),
587-588.
ISSN 1474-1776 .
IF: 57.000.
PMID:
28450744
TICHÝ, M., S. SMOLEN, E. TLOUŠŤOVÁ, R. POHL, T. OŽDIAN, K. HEJTMÁNKOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK.
Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.
Journal of Medicinal Chemistry.
2017,
60(6),
2411-2424.
ISSN 0022-2623.
IF: 5.589.
PMID:
28221790
CHROMÁ, K., M. MISTRÍK, P. MOUDRÝ, J. GURSKÝ, M. LIPTAY, R. STRAUSS, Z. ŠKROTT, R. VRTEL, J. BARTKOVA, J. KRAMARA a J. BÁRTEK.
Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress.
Oncogene.
2017,
36(17),
2405-2422.
ISSN 0950-9232 .
IF: 7.932.
PMID:
27841863
NAJDEKR, L., D. FRIEDECKÝ, R. TAUTENHAHN, T. PLUSKAL, J. WANG, Y. HUANG a T. ADAM.
Influence of Mass Resolving Power in Orbital Ion-Trap Mass Spectrometry-Based Metabolomics.
Analytical Chemistry.
2016,
88(23),
11429-11435.
ISSN 0003-2700.
IF: 6.320.
PMID:
27809493
SKOLOUDIK, D., P. BARTOVA, J. MASKOVA, P. DUSEK, J. BLAHUTA, K. LANGOVÁ, D. WALTER a R. HERZIG.
Transcranial Sonography of the Insula: Digitized Image Analysis of Fusion Images with Magnetic Resonance.
Ultraschall in der Medizin .
2016,
37(6),
604-608.
ISSN 0172-4614 .
IF: 3.452.
PMID:
27486795
JIRAVOVÁ, J., K. BARTOŇ TOMÁNKOVÁ, M. HARVANOVÁ, L. MALINA, J. MALOHLAVA, L. LUHOVA, A. PANACEK, B. MANIŠOVÁ a H. KOLÁŘOVÁ.
The effect of silver nanoparticles and silver ions on mammalian and plant cells in vitro.
Food and Chemical Toxicology.
2016,
96(-),
50-61.
ISSN 0278-6915 .
IF: 3.778.
PMID:
27456126
BÜRGLOVÁ, K., S. OKOROCHENKOV a J. HLAVÁČ.
Efficient Route to Deuterated Aromatics by the Deamination of Anilines.
Organic Letters.
2016,
18(14),
3342-3345.
ISSN 1523-7060.
IF: 6.579.
PMID:
27378277
GALANOS, P., K. VOUGAS, D. WALTER, A. POLYZOS, A. MAYA-MENDOZA, E. HAAGENSEN, A. KOKKALIS, F. ROUMELIOTI, S. GAGOS, M. TZETIS, B. CANOVAS, A. IGEA, A. AHUJA, R. ZELLWEGER, S. HAVAKI, E. KANAVAKIS, D. KLETSAS, I. RONINSON, S. GARBIS, M. LOPES, A. NEBREDA, D. THANOS, J. BLOW, P. TOWNSEND, C. SORENSEN, J. BÁRTEK a V. GOURGOULIS.
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.
Nature Cell Biology.
2016,
18(7),
777-789.
ISSN 1465-7392 .
IF: 20.060.
PMID:
27323328
SMUTNY, T., A. NOVÁ, M. DRECHSLEROVA, A. CARAZO, L. HYRSOVA, Z. HRUSKOVA, J. KUNEŠ, M. POUR, M. SPULAK a P. PAVEK.
2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.
Journal of Medicinal Chemistry.
2016,
59(10),
4601-10.
ISSN 0022-2623.
IF: 6.259.
PMID:
27145071
FOGLAROVA, M., J. CHMELAR, G. HUERTA-ANGELES, H. VAGNEROVA, J. KULHANEK, K. BARTOŇ TOMÁNKOVÁ, A. MINARIK a V. VELEBNY.
Water-insoluble thin films from palmitoyl hyaluronan with tunable properties.
Carbohydrate Polymers.
2016,
144,
68-75.
ISSN 0144-8617.
IF: 4.811.
PMID:
27083794
GILLILAND, C.T., D. ZUK, P. KOCIS, M. JOHNSON, S. HAY, M. HAJDÚCH, F. BIETRIX, G. AVERSA, C.P. AUSTIN a A.E. USSI.
Putting translational science on to a global stage.
Nature Reviews Drug Discovery.
2016,
15,
217-219.
ISSN 1474-1776.
IF: 57.000.
PMID:
27032820
MOUDRÝ, P., K. WATANABE, K. WOLANIN, J. BARTKOVA, I. WASSING, S. WATANABE, R. STRAUSS, R.S. PEDERSEN, V. OESTERGAARD, M. LISBY, M. ANDUJAR-SANCHEZ, A. MAYA-MENDOZA, F. ESASHI, J. LUKÁŠ a J. BÁRTEK.
TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity.
Journal of Cell Biology.
2016,
212(3),
281-288.
ISSN 0021-9525 .
IF: 7.955.
PMID:
26811421
MISTRÍK, M., E. VESELÁ, T. FÜRST, H. HANZLIKOVA, I. FRYDRYCH, J. GURSKÝ, D. MAJERA a J. BÁRTEK.
Cells and Stripes: A novel quantitative photo-manipulation technique.
Scientific Reports.
2016,
6(-),
Article Number: 19567.
ISSN 2045-2322.
IF: 4.259.
PMID:
26777522
BRAUER, R., J. TURECKOVA, I. KANCHEV, M. KHOYLOU, J. ŠKARDA, J. PROCHAZKA, F. SPOUTIL, I.M. BECK, O. ŽBODÁKOVÁ, P. KASPAREK, V. KORINEK, K. CHALUPSKÝ, T. KARHU, K.H. HERZIG, M. HAJDÚCH, M. GREGOR a R. SEDLÁČEK.
MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function.
Mucosal Immunology.
2016,
9(4),
974-985.
ISSN 1933-0219.
IF: 7.478.
PMID:
26555704
SURINOVA, S., M. CHOI, S. TAO, P.J. SCHÜFFLER, C.Y.. CHANG, T. CLOUGH, K. VYSLOUŽIL, M. KHOYLOU, J. SROVNAL, Y. LIU, M. MATONDO, R. HÜTTENHAIN, H. WEISSER, J.M. BUHMANN, M. HAJDÚCH, H. BRENNER, O. VITEK a R. AEBERSOLD.
Prediction of colorectal cancer diagnosis based on circulating plasma proteins.
EMBO Molecular Medicine.
2015,
7(9),
1166-1178.
ISSN 1757-4676 .
IF: 9.547.
PMID:
26253081
SURINOVA, S., L. RADOVÁ, M. CHOI, J. SROVNAL, H. BRENNER, O. VITEK, M. HAJDÚCH a R. AEBERSOLD.
Non-invasive prognostic protein biomarker signatures associated with colorectal cancer.
EMBO Molecular Medicine.
2015,
7(9),
1153-1165.
ISSN 1757-4676.
IF: 9.547.
PMID:
26253080
KOMIS, G., M. MISTRÍK, O. SAMAJOVA, M. OVECKA, J. BÁRTEK a J. SAMAJ.
Superresolution live imaging of plant cells using structured illumination microscopy.
Nature Protocols.
2015,
10(8),
1248-1263.
ISSN 1754-2189.
IF: 9.646.
PMID:
26203822
DIETLEIN, F., B. KALB, M. JOKIC, E. NOLL, A. STRONG, L. THARUN, L. OZRETIC, H. KUNSTLINGER, K. KAMBARTEL, W. RANDERATH, C. JUNGST, A. SCHMITT, A. TORGOVNICK, A. RICHTERS, D. RAUH, F. SIEDEK, T. PERSIGEHL, C. MAUCH, J. BARTKOVA, A. BRADLEY, M. SPRICK, A. TRUMPP, R. RAD, D. SAUR, J. BÁRTEK, J. WOLF, R. BUTTNER, R. THOMAS a H. REINHARDT.
A Synergistic Interaction between Chk1-and MK2 Inhibitors in KRAS-Mutant Cancer.
Cell.
2015,
162(1),
146-159.
ISSN 0092-8674.
IF: 28.710.
PMID:
26140595
FORMARA, O., J.J. BARTEK, A. RAHBAR, J. ODEBERG, Z. KHAN, I. PEREDO, P. HAMERLIK, J. BÁRTEK, G. STRAGLIOTTO, N. LANDAZURI a C. SODERBERG-NAUCLER.
Cytomegalovirus infection induces a stem cell phenotype in human primary glioblastoma cells: prognostic significance and biological impact.
Cell Death and Differentiation.
2016,
23(2),
261-269.
ISSN 1350-9047.
IF: 8.339.
PMID:
26138445
ZHAI, C., D. SUMMER, C. RANGGER, G. FRANSSEN, P. LAVERMAN, H. HAAS, M. PETŘÍK, R. HAUBNER a C. DECRISTOFORO.
Novel Bifunctional Cyclic Chelator for (89)Zr Labeling-Radiolabeling and Targeting Properties of RGD Conjugates.
Molecular Pharmaceutics.
2015,
12(6),
2142-2150.
ISSN 1543-8384.
IF: 4.342.
PMID:
25941834
DAS, V., F. BRUZZESE, P. KONEČNÝ, F. IANNELLI, A. BUDILLON a M. HAJDÚCH.
Pathophysiologically relevant in vitro tumor models for drug screening.
Drug Discovery Today.
2015,
20(7),
848-55.
ISSN 1359-6446.
IF: 5.625.
PMID:
25908576
XU, G., J. CHAPMAN, I. BRANDSMA, J. YUAN, M. MISTRÍK, P. BOUWMAN, J. BARTKOVA, E. GOGOLA, D. WARMERDAM, M. BAZARAS, J. JASPERS, K. WATANABE, M. PIETERSE, K. KERSBERGEN, W. SOL, P. CELIE, P. SCHOUTEN, B. VAN DEN BROEK, A. SALMAN, M. NIEUWLAND, I. DE RINK, J. DE RONDE, K. JALINK, S. BOULTON, J. CHEN, D. VAN GENT, J. BÁRTEK, J. JONKERS, P. BORST a S. ROTTENBERG.
REV7 counteracts DNA double-strand break resection and affects PARP inhibition.
Nature.
2015,
521(7553),
541-544.
ISSN 0028-0836.
IF: 38.138.
PMID:
25799992
KANU, N., E. GRONROOS, P.. MARTINEZ, R.A. BURRELL, X.Y. GOH, J. BARTKOVA, A. MAYA-MENDOZA, M. MISTRÍK, A.J. ROWAN, H. PATEL, A. RABINOWITZ, P. EAST, G. WILSON, C.R. SANTOS, N. MCGRANAHAN, S. GULATI, M. GERLINGER, N.J. BIRKBAK, T. JOSHI, L.B. ALEXANDROV, M.R. STRATTON, T. POWLES, N. MATTHEWS, P.A. BATES, A. STEWART, Z. SZALLASI, J. LARKIN, J. BÁRTEK a C. SWANTON.
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair.
Oncogene.
2015,
34(46),
5699-5708.
ISSN 0950-9232.
IF: 7.932.
PMID:
25728682
DAS, V., J. DVOŘANOVÁ ŠTĚPÁNKOVÁ, M. HAJDÚCH a J.H. MILLER.
Role of tumor hypoxia in acquisition of resistance to microtubule-stabilizing drugs.
Biochimica et Biophysica Acta Reviews on Cancer.
2015,
1855(2),
172-182.
ISSN 0304-419X.
IF: 7.841.
PMID:
25662312
OKOROCHENKOV, S., K. BÜRGLOVÁ, I. POPA a J. HLAVÁČ.
Solid-Supported Hydrazone of 4-(4 '-Formyl-3 '-methoxyphenoxy)butyric Acid As a New Traceless Linker for Solid-Phase Synthesis.
Organic Letters.
2015,
17(2),
180-183.
ISSN 1523-7060.
IF: 6.732.
PMID:
25536078
KULIHA, M., M. ROUBEC, V. PROCHAZKA, T. JONSZTA, T. HRBAC, J. HAVELKA, A. GOLDIROVA, K. LANGOVÁ, R. HERZIG a D. SKOLOUDIK.
Randomized clinical trial comparing neurological outcomes after carotid endarterectomy or stenting.
British Journal of Surgery.
2015,
102(3),
194-201.
ISSN 0007-1323.
IF: 5.596.
PMID:
25511816
CHRISTENSEN, C., J. BARTKOVA, M. MISTRÍK, A. HALL., M.K. LANGE, U. RALFKIÆR, J. BÁRTEK a P. GULDBERG.
A short acidic motif in ARF guards against mitochondrial dysfunction and melanoma susceptibility.
Nature Communications.
2014,
5(5348),
-.
ISSN 2041-1723.
IF: 11.470.
PMID:
25370744
SNÁŠEL, J., P. NAUŠ, J. DOSTÁL, A. HNÍZDA, J. FANFRLÍK, J. BRYNDA, A. BOURDERIOUX, M. DUŠEK, H. DVOŘÁKOVÁ, J. STOLAŘÍKOVÁ, H. ZÁBRANSKÁ, R. POHL, P. KONEČNÝ, P. DŽUBÁK, I. VOTRUBA, M. HAJDÚCH, P. ŘEZÁČOVÁ, V. VEVERKA, M. HOCEK a I. PICHOVÁ.
Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides.
Journal of Medicinal Chemistry.
2014,
57(20),
8268-8279.
ISSN 0022-2623.
IF: 5.447.
PMID:
25259627
KISSELJOVA, K., P. SMYSLOVÁ a V. KRCHŇÁK.
Benzhydrylamines via Base-Mediated Intramolecular sp(3) C-Arylation of N-Benzyl-2-nitrobenzenesulfonamides-Advanced Intermediates for the Synthesis of Nitrogenous Heterocycles.
ACS Combinatorial Science.
2014,
16(10),
573-577.
ISSN 2156-8952.
IF: 3.032.
PMID:
25180543
OKA, Y., H. VARMARK, K. VITTING-SEERUP, P. BELI, J. WAAGE, A. HAKOBYAN, M. MISTRÍK, C. CHOUDHARY, M. ROHDE, S. BEKKER-JENSEN a N. MAILAND.
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells.
EMBO Reports.
2014,
15(9),
956-964.
ISSN 1469-221X.
IF: 9.055.
PMID:
25092792
KUMAR, A., M. MAZZANTI, M. MISTRÍK, M. KOSAR, G.V. BEZNOUSSENKO, A.A. MIRONOV, M. GARRE, D. PARAZZOLI, G. SHIVASHANKAR, G. SCITA, J. BÁRTEK a M. FOIANI.
ATR Mediates a Checkpoint at the Nuclear Envelope in Response to Mechanical Stress.
Cell.
2014,
158(3),
633-646.
ISSN 0092-8674.
IF: 32.242.
PMID:
25083873
SMYSLOVÁ, P., K. KISSELJOVA a V. KRCHŇÁK.
Base-Mediated Intramolecular C- and N-Arylation of N,N-Disubstituted 2-Nitrobenzenesulfonamides: Advanced Intermediates for the Synthesis of Diverse Nitrogenous Heterocycles.
ACS Combinatorial Science.
2014,
16(9),
500-505.
ISSN 2156-8952.
IF: 3.032.
PMID:
25076047
LEMROVÁ, B., P. SMYSLOVÁ, I. POPA, T. OŽDIAN, P. ZAJDEL a M. SOURAL.
Directed Solid-Phase Synthesis of Trisubstituted Imidazo[4,5-c]pyridines and Imidazo[4,5-b]pyridines.
ACS Combinatorial Science.
2014,
16(10),
558-565.
ISSN 2156-8952.
IF: 3.032.
PMID:
25046560
FÜLÖPOVÁ, V. a V. KRCHŇÁK.
Solid-Phase Synthesis of Trisubstituted 2,5-Dihydrobenzo[f][1,2,5]thiadiazepine 1,1-Dioxide Derivatives.
ACS Combinatorial Science.
2014,
16(8),
412-420.
ISSN 2156-8952.
IF: 3.032.
PMID:
24884092
POSPÍŠILOVÁ, D., D. HOLUB, Z. ŽIDOVÁ, L. SULOVSKÁ, J. HOUDA, V. MIHÁL, I. HADAČOVÁ, L. RADOVÁ, P. DŽUBÁK, M. HAJDÚCH, V. DIVOKÝ a M. HORVÁTHOVÁ.
Hepcidin levels in Diamond-Blackfan anemia reflect erythropoietic activity and transfusion dependency.
Haematologica.
2014,
99(7),
e118-121.
ISSN 0390-6078.
IF: 5.814.
PMID:
24727814
MCMASTER, C., V. FÜLÖPOVÁ, I. POPA, M. GREPL a M. SOURAL.
Solid-Phase Synthesis of Anagrelide Sulfonyl Analogues.
ACS Combinatorial Science.
2014,
16(5),
221-224.
ISSN 2156-8952.
IF: 3.032.
PMID:
24725158
VENTOSA-ANDRÉS, P., L. HRADILOVÁ a V. KRCHŇÁK.
Privileged Structures as Peptide Backbone Constraints: Polymer-Supported Stereoselective Synthesis of Benzimidazolinopiperazinone Peptides.
ACS Combinatorial Science.
2014,
16(7),
359-366.
ISSN 2156-8952.
IF: 3.032.
PMID:
24725105
KOMIS, G., M. MISTRÍK, O. SAMAJOVA, A. DOSKOCILOVA, M. OVECKA, P. ILLES, J. BÁRTEK a J. SAMAJ.
Dynamics and Organization of Cortical Microtubules as Revealed by Superresolution Structured Illumination Microscopy.
Plant Physiology.
2014,
165(1),
129-148.
ISSN 0032-0889.
IF: 6.841.
PMID:
24686112
CANKAŘOVÁ, N., A.L. VENIA a V. KRCHŇÁK.
Polymer-Supported Stereoselective Synthesis of Tetrahydrobenzopyrazino-thiadiazinone Dioxides via N-Sulfonyl Iminiums.
ACS Combinatorial Science.
2014,
16(6),
293-302.
ISSN 2156-8952.
IF: 3.032.
PMID:
24575715
RANC, V., Z. MARKOVÁ, M. HAJDÚCH, R. PRUCEK, L. KVÍTEK, J. KAŠLÍK, K. ŠAFÁŘOVÁ a R. ZBOŘIL.
Magnetically Assisted Surface-Enhanced Raman Scattering Selective Determination of Dopamine in an Artificial Cerebrospinal Fluid and a Mouse Striatum Using Fe3O4/Ag Nanocomposite.
Analytical Chemistry.
2014,
86(6),
2939-2946.
ISSN 0003-2700.
IF: 5.636.
PMID:
24555681
BHATTACHARYYA, T., R. REIFOVA, S. GREGOROVA, P. SIMECEK, V. GERGELITS, M. MISTRÍK, I. MARTINCOVA, J. PIALEK a J. FOREJT.
X Chromosome Control of Meiotic Chromosome Synapsis in Mouse Inter-Subspecific Hybrids.
PLOS Genetics.
2014,
10(2),
-.
ISSN 1553-7404.
IF: 7.528.
PMID:
24516397
NAUŠ, P., O. CALETKOVÁ, P. KONEČNÝ, P. DŽUBÁK, K. BOGDANOVÁ, M. KOLÁŘ, J. VRBKOVÁ, L. SLAVĚTÍNSKÁ, E. TLOUŠŤOVÁ, P. PERLÍKOVÁ, M. HAJDÚCH a M. HOCEK.
Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides.
Journal of Medicinal Chemistry.
2014,
57(3),
1097-1110.
ISSN 0022-2623.
IF: 5.447.
PMID:
24397620
YAMADA, M., K. WATANABE, M. MISTRÍK, E. VESELÁ, I. PROTIVÁNKOVÁ, N. MAILAND, M. LEE, H. MASAI, J. LUKÁŠ a J. BÁRTEK.
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress.
Genes & Development.
2013,
27(22),
2459-2472.
ISSN 0890-9369.
IF: 12.639.
PMID:
24240236
BÁRTEK, J., M. MISTRÍK a J. BARTKOVA.
Androgen receptor signaling fuels DNA repair and radioresistance in prostate cancer.
Cancer Discovery.
2013,
3(11),
1222-1224.
ISSN 2159-8274.
IF: 15.929.
PMID:
24203954
DINANT, C., G. AMPATZIADIS-MICHAILIDIS, H. LANS, M. TRESINI, A. LAGAROU, M. GROSBART, A. THEI, CAPPELLEN, W. VAN, H. KIMURA, J. BÁRTEK, M. FOUSTERI, A.B. HOUTSMULLER, W. VERMEULEN a J.A. MARTEIJN.
Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restart after UV-Induced DNA Damage.
Molecular Cell.
2013,
51(4),
469-479.
ISSN 1097-2765.
IF: 14.464.
PMID:
23973375
RANC, V., J. SROVNAL, L. KVÍTEK a M. HAJDÚCH.
Discrimination of circulating tumor cells of breast cancer and colorectal cancer from normal human mononuclear cells using Raman spectroscopy.
Analyst.
2013,
138(20),
5983-5988.
ISSN 0003-2654.
IF: 3.906.
PMID:
23945652
VOCKERODT, M., W. WEI, E. NAGY, Z. PROUZOVÁ, A. SCHRADER, D. KUBE, M. ROWE, C. WOODMAN a P. MURRAY.
Suppression of the LMP2A target gene, EGR-1, protects Hodgkin's lymphoma cells from entry to the EBV lytic cycle.
Journal of Pathology.
2013,
230(4),
399-409.
ISSN 0022-3417.
IF: 7.330.
PMID:
23592216
BURRELL, R.A., S.E. MCCLELLAND, D. ENDESFELDER, P. GROTH, M.C.. WELLER, N. SHAIKH, E. DOMINGO, N. KANU, S.M. DEWHURST, E. GRONROOS, S.K. CHEW, A.J. ROWAN, A. SCHENK, M. SHEFFER, M. HOWELL, M. KSCHISCHO, A. BEHRENS, T. HELLEDAY, J. BÁRTEK, I.R. TOMLINSON a C. SWANTON.
Replication stress links structural and numerical cancer chromosomal instability.
Nature.
2013,
494(7438),
492-496.
ISSN 0028-0836.
IF: 42.351.
PMID:
23446422
HÜTTENHAIN, R., S. SURINOVA, R. OSSOLA, Z. SUN, D. CAMPBELL, F. CERCIELLO, R. SCHIESS, D. BAUSCH-FLUCK, G. ROSENBERGER, J. CHEN, O. RINNER, U. KUSEBAUCH, M. HAJDÚCH, R.L. MORITZ, B. WOLLSCHEID a R. AEBERSOLD.
N-glycoprotein SRMAtlas: a resource of mass spectrometric assays for N-glycosites enabling consistent and multiplexed protein quantification for clinical applications.
Molecular & Cellular Proteomics.
2013,
12(4),
1005-1016.
ISSN 1535-9476.
IF: 7.254.
PMID:
23408683
SKOLOUDIK, D., M. KULIHA, M. ROUBEC, T. JONSZTA, V. PROCHAZKA, K. LANGOVÁ a R. HERZIG.
Safety and Efficacy of Endovascular Sonolysis Using the EkoSonic Endovascular System in Patients with Acute Stroke.
American Journal of Neuroradiology.
2013,
34(7),
1401-1406.
ISSN 0195-6108.
IF: 3.675.
PMID:
23370469
VRBA, J., R. GAZAK, M. KUZMA, B. PAPOUSKOVA, J. VACEK, M. WEISZENSTEIN, V. KREN a J. ULRICHOVÁ.
A Novel Semisynthetic Flavonoid 7‑O‑Galloyltaxifolin Upregulates Heme Oxygenase‑1 in RAW264.7 Cells via MAPK/Nrf2 Pathway.
Journal of Medicinal Chemistry.
2013,
56(3),
856-866.
ISSN 0022-2623.
IF: 5.480.
PMID:
23294286
ROUBEC, M., M. KULIHA, V. PROCHAZKA, J. KRAJCA, J. CZERNY, T. JONSZTA, A. KRAJINA, D. SANAK, K. LANGOVÁ, R. HERZIG a D. SKOLOUDIK.
A controlled trial of revascularization in acute stroke.
Radiology.
2013,
266(3),
871-878.
ISSN 0033-8419.
IF: 6.214.
PMID:
23232292
GUDJONSSON, T., M. ALTMEYER, V. SAVIC, L. TOLEDO, C. DINANT, M. GROFTE, J. BARTKOVA, M. POULSEN, Y. OKA, S. BEKKER-JENSEN, N. MAILAND, B. NEUMANN, J. HERICHE, R. SHEARER, D. SAUNDERS, J. BÁRTEK, J. LUKÁŠ a C. LUKAS.
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes.
Cell.
2012,
150(4),
697-709.
ISSN 0092-8674.
IF: 31.957.
PMID:
22884692
DAUGAARD, M., A. BAUDE, K. FUGGER, L.K. POVLSEN, H. BECK, C. SORENSEN, N. PETERSEN, P. SORENSEN, C. LUKAS, J. BÁRTEK, J. LUKÁŠ, M. ROHDE a M. JAATTELA.
LEDGF (p75) promotes DNA-end resection and homologous recombination.
Nature Structural & Molecular Biology.
2012,
19(8),
803-810.
ISSN 1545-9993.
IF: 11.902.
PMID:
22773103
FALCK, J., J. FORMENT, J. COATES, M. MISTRÍK, J. LUKÁŠ, J. BÁRTEK a S.P. JACKSON.
CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination.
EMBO Reports.
2012,
13(6),
561-568.
ISSN 1469-221X.
IF: 7.189.
PMID:
22565321
PETŘÍK, M., G. FRANSSEN, H. HAAS, P. LAVERMAN, C. HÖRTNAGL, M. SCHRETTL, A. HELBOK, C. LASS-FLÖRL a C. DECRISTOFORO.
Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging.
European Journal of Nuclear Medicine and Molecular Imaging.
2012,
39(7),
1175-1183.
ISSN 1619-7070.
IF: 5.114.
PMID:
22526953
HAMERLIK, P., J. LATHIA, R. RASMUSSEN, B. WU, J. BARTKOVA, M. LEE, P. MOUDRÝ, J.J. BARTEK, W. FISCHER, J. LUKÁŠ, J.N. RICH a J. BÁRTEK.
Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth.
Journal of Experimental Medicine.
2012,
209(3),
507-520.
ISSN 0022-1007.
IF: 13.214.
PMID:
22393126
BÁRTEK, J., M. MISTRÍK a J. BARTKOVA.
Thresholds of replication stress signaling in cancer development and treatment.
Nature Structural & Molecular Biology.
2012,
19(1),
5-7.
ISSN 1545-9993.
IF: 11.902.
PMID:
22218289
JANEČKOVÁ, H., K. HRON, P. WOJTOWICZ, E. HLIDKOVA, A. BARESOVA, D. FRIEDECKÝ, L. ŽÍDKOVÁ, P. HORNIK, D. BEHULOVA, D. PROCHAZKOVA, H. VINOHRADSKA, K. PESKOVA, P. BRUHEIM, V. SMOLKA, S. STASTNA a T. ADAM.
Targeted metabolomic analysis of plasma samples for the diagnosis of inherited metabolic disorders.
Journal of Chromatography A.
2012,
1226(-),
11-17.
ISSN 1873-3778.
IF: 4.612.
PMID:
22018716
BEYER, I., R.V. RENSBURG, R. STRAUSS, L. ZONG-YI, W. HONGJIE, J. PERSSON, R. YUMUL, F. QINGHUA, H. SONG, J. BÁRTEK, P. FENDER a A. LIEBER.
Epithelial junction opener JO-1 improves monoclonal antibody therapy of cancer.
Cancer Research.
2011,
71(22),
7080-7090.
ISSN 0008-5472.
IF: 7.856.
PMID:
21990319
SERIO, G., V. MARGARIA, S. JENSEN, A. OLDANI, J. BÁRTEK, F. BUSSOLINO a L. LANZETTI.
Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores.
Proceedings of the National Academy of Sciences of the United States of America.
2011,
108(42),
17337-17342.
ISSN 0027-8424.
IF: 9.681.
PMID:
21987812
BOURDERIOUX, A., P. NAUŠ, P. PERLÍKOVÁ, R. POHL, I. PICHOVÁ, I. VOTRUBA, P. DŽUBÁK, P. KONEČNÝ, M. HAJDÚCH, K.M. STRAY, T. WANG, A.S. RAY, J.Y. FENG, G. BIRKUS, T. CIHLÁŘ a M. HOCEK.
Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines.
Journal of Medicinal Chemistry.
2011,
54(15),
5498-5507.
ISSN 0022-2623.
IF: 5.248.
PMID:
21711054
BÁRTEK, J. a J. LUKÁŠ.
DNA REPAIR Cyclin D1 multitasks.
Nature.
2011,
474(7350),
171-172.
ISSN 0028-0836.
IF: 36.280.
PMID:
21654798
JORDA, R., L. HAVLICEK, I.W. MCNAE, M.D. WALKINSHAW, J. VOLLER, A. STURC, J. NAVRATILOVA, M. KUZMA, M. MISTRÍK, J. BÁRTEK, M. STRNAD a V. KRYŠTOF.
Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity.
Journal of Medicinal Chemistry.
2011,
54(8),
2980-2993.
ISSN 0022-2623.
IF: 5.248.
PMID:
21417417
VRZALIKOVA, K., M. VOCKERODT, S. LEONARD, A. BELL, W. WEI, A. SCHRADER, K. WRIGHT, D. KUBE, M. ROWE, C. WOODMAN a P. MURRAY.
Down-regulation of BLIMP1α by the EBV oncogene, LMP-1, disrupts the plasma cell differentiation program and prevents viral replication in B cells: implications for the pathogenesis of EBV-associated B-cell lymphomas.
Blood.
2011,
117(22),
5907-5917.
ISSN 0006-4971.
IF: 9.898.
PMID:
21411757
LÖFFLER, H., A. FECHTER, M. MATUSZEWSKA, R. SAFFRICH, M. MISTRÍK, J. MARHOLD, C. HORNUNG, F. WESTERMANN, J. BÁRTEK a A. KRÄMER.
Cep63 Recruits Cdk1 to the Centrosome: Implications for Regulation of Mitotic Entry, Centrosome Amplification, and Genome Maintenance.
Cancer Research.
2011,
71(6),
2129-2139.
ISSN 0008-5472.
IF: 7.856.
PMID:
21406398
LUKAS, C., V. SAVIC, S. BEKKER-JENSEN, C. DOIL, B. NEUMANN, R.S. PEDERSEN, M. GROFTE, K.L. CHAN, I.D. HICKINSON a J. BÁRTEK.
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress.
Nature Cell Biology.
2011,
13(3),
243-253.
ISSN 1465-7392.
IF: 19.488.
PMID:
21317883
WOJTOWICZ, P., J. ZROSTLÍKOVÁ, T. KOVALCZUK, J. SCHUREK a T. ADAM.
Evaluation of comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry for the diagnosis of inherited metabolic disorders using an automated data processing strategy.
Journal of Chromatography A.
2010,
1217(51),
8054-8061.
ISSN 0021-9673.
IF: 4.194.
PMID:
20961553
BÁRTEK, J., M. MISTRÍK a J. BARTKOVA.
Long-distance inflammatory and genotoxic impact of cancer in vivo.
Proceedings of the National Academy of Sciences of the United States of America.
2010,
107(42),
17861-17862.
ISSN 0027-8424.
IF: 9.771.
PMID:
20926747
BÁRTEK, J., P. HAMERLIK a J. LUKÁŠ.
On the origin of prostate fusion oncogenes.
Nature Genetics.
2010,
42(8),
647-648.
ISSN 1061-4036.
IF: 36.377.
PMID:
20664645
BOUWMAN, P., A. ALY, J.M. ESCANDELL, M. PIETERSE, J. BARTKOVA, H.. VAN DER GULDEN, S. HIDDINGH, M. THANASOULA, A. KULKARNI, Q. YANG, B.G. HAFFTY, J. TOMMISKA, C. BLOMQVIST, R. DRAPKIN, D.J. ADAMS, H. NEVANLINNA, J. BÁRTEK, M. TARSOUNAS, S. GANESAN a J. JONKERS.
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
Nature Structural & Molecular Biology.
2010,
17(6),
688-695.
ISSN 1545-9993.
IF: 13.685.
PMID:
20453858
KOSINA, P., A. DOKOUPILOVA, K. JANDA, K. SLADKOVA, P. SILBEROVA, V. PIVODOVÁ a J. ULRICHOVÁ.
Effect of Silybum marianum fruit constituents on the healthstatus of rabbits in repeated 42-day fattening experiment.
Animal Feed Science and Technology.
2017,
223(2017),
128-140.
ISSN 0377-8401.
IF: 2.143.
SCHUTZNEROVA, E., A. OLIVER, A. PRIBYLKA a V. KRCHŇÁK.
Solid-Phase Synthesis of Tetramic Acid via Resin-Bound Enol Ethers as a Privileged Scaffold in Drug Discovery.
Advanced Synthesis and catalysis.
2018,
360(19),
3693-3699.
ISSN 1615-4150.
IF: 5.123.
HAVLIK, J., H. RAABOVA, M. GULKA, V. PETRAKOVA, M. KRECMANOVA, V. MAŠEK, P. LOUSA, J. STURSA, H. BOYEN, M. NESLADEK a P. CIGLER.
Benchtop Fluorination of Fluorescent Nanodiamonds on a Preparative Scale: Toward Unusually Hydrophilic Bright Particles.
Advanced Functional Materials.
2016,
26(23),
4134-4142.
ISSN 1616-301X.
IF: 12.124.
ZOPPELARO, G., A. KOLOKITHAS-NTOUKAS, K. POLAKOVA, J. TUCEK, R. ZBOŘIL, G. LOUDOS, E. FRAGOGEORGI, C. DIWOKY, K. TOMÁNKOVÁ, K. AVGOUSTAKIS, D. KOUZOUDIS a A. BAKANDRITSOS.
Theranostics of Epitaxially Condensed Colloidal Nanocrystal Clusters, through a Soft Biomineralization Route.
Chemistry of Materials.
2014,
26(6),
2062-2074.
ISSN 0897-4756.
IF: 8.354.
KRIEGELSTEINOVÁ, P., B. LEMROVÁ, V. RUČILOVÁ a M. SOURAL.
Copper‐Free Solid‐Phase Synthesis of Triazolo[1,5‐a][1,4]diazepin‐6‐ones.
Advanced Synthesis & Catalysis.
2021,
363(4),
1112-1119.
ISSN 1615-4150.
IF: 5.851.
