IMTM

HODOŇ, J., L. BORKOVÁ, J. POKORNÝ, A. KOZAKOVA a M. URBAN. Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research. European Journal of Medicinal Chemistry. 2019, -, -. ISSN 0223-5234. IF: 4.833. PMID: 31499360

KADLECOVA, A., B. MAKOVA, M. ARTAL-SANZ, M. STRNAD a J. VOLLER. The plant hormone kinetin in disease therapy and healthy aging. Ageing Rsearch Reviews. 2019, -, -. ISSN 1568-1637. IF: 10.390. PMID: 31479763

VANZO, R., J. BARTKOVA, J. MERCHUT-MAYA, A. HALL., J. BOUCHAL, L. DYRSKJOT, L. FRANKEL, V.G. GORGOULIS, A. MAYA-MENDOZA, M. JAATTELA a J. BÁRTEK. Autophagy role(s) in response to oncogenes and DNA replication stress. Cell Death and Differentiation. 2019, -, -. ISSN 1350-9047. IF: 8.086. PMID: 31409894

VANDA, D., P. ZAJDEL a M. SOURAL. Imidazopyridine-based selective and multifunctional ligands of biological targets associated with psychiatric and neurodegenerative diseases. European Journal of Medicinal Chemistry. 2019, -, -. ISSN 0223-5234. IF: 4.833. PMID: 31404862

VOUGAS, K., T. SAKELAROPOULOS, A. KOTSINAS, G. FOUKAS, A. NTARGARAS, F. KOINIS, A. POLYZOS, V. MYRIANTHOPOULOS, H. ZHOU, S. NARANG, V. GEORGOULIAS, L. ALEXOPOULOS, I. AIFANTIS, P. TOWNSEND, P. SFIKAKIS, R. FITZGERALD, D. THANOS, J. BÁRTEK, R. PETTY, A. TSIRIGOS a V.G. GORGOULIS. Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining. Pharmacology & Therapeutics. 2019, -, -. ISSN 0163-7258. IF: 9.396. PMID: 31374225

LUPINO, L., T. PERRY, S. MARGIELEWSKA, R. HOLLOWS, M. IBRAHIM, M. CARE, J. ALLEGOOD, R. TOOZE, R. SABBADINI, G. REYNOLDS, R. BICKNELL, Z. RUDZKI, Y. LIN HOCK, U. ZANETTO, W. WEI, W. SIMMONS, S. SPIEGEL, C.B.J. WOODMAN, M. ROWE, K. VRZALIKOVA a P. MURRAY. Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma. Leukemia. 2019, -, -. ISSN 0887-6924. IF: 10.023. PMID: 31097785

GARIC, D., J.B. DE SANCTIS, J. SHAH, D. DUMUT a D. RADZIOCH. Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain. Progress in Lipid Research. 2019, 74, 130-144. ISSN 0163-7827. IF: 8.435. PMID: 30876862

BARTHELDYOVA, E., P. TURANEK KNOTIGOVA, K. ZACHOVÁ, J. MASEK, P. KULICH, R. EFFENBERG, D. ZYKA, F. HUBATKA, J. KOTOUCEK, H. CELECHOVSKA, R. HEZOVA, A. TOMECKOVA, E. MASKOVA, M. FOJTIKOVA, S. MACAULAY, P. BYSTRICKY, E. PAULOVICOVA, L. DROZ, M. LEDVINA, M. RAŠKA a J. TURANEK. N-Oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: Synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells. Carbohydrate Polymers. 2019, 207, 521-532. ISSN 0144-8617. IF: 5.158. PMID: 30600036

DE LA FUENTE, G., F. TRALDI, J. ŠIROKÁ, A. KRETOWSKI, M. CIBOROWSKI, A. OTERO, C. BARBAS a J. GODZIEN. Characterization and annotation of oxidized glycerophosphocholines for non-targeted metabolomics with LC-QTOF-MS data. Analytica Chimica Acta. 2018, 1037, 358-369. ISSN 0003-2670. IF: 5.123. PMID: 30292312

TOKARENKO, A., B. LIŠKOVÁ, S. SMOLEN, N. TÁBORSKÁ, M. TICHÝ, S. GURSKÁ, P. PERLÍKOVÁ, I. FRYDRYCH, E. TLOUŠŤOVÁ, P. ZNOJEK, H. MERTLIKOVA-KAISEROVA, L. POSTOVA SLAVETINSKA, R. POHL, B. KLEPETAROVA, N. KHALID, Y. WENREN, R. LAPOSA, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides. Journal of Medicinal Chemistry. 2018, 61(20), 9347-9359. ISSN 0022-2623. IF: 6.253. PMID: 30281308

KARLÍKOVÁ, R., J. ŠIROKÁ, M. MECH, D. FRIEDECKÝ, H. JANEČKOVÁ, L. MÁDROVÁ, F. HRDINOVA, Z. DRABKOVA, O. DOBESOVA, T. ADAM a P. JAHN. Newborn foal with atypical myopathy. Journal of Veterinary Internal Medicine. 2018, 32(5), 1768-1772. ISSN 0891-6640. IF: 2.185. PMID: 30216546

MAYA-MENDOZA, A., P. MOUDRÝ, J. MERCHUT-MAYA, M. LEE, R. STRAUSS a J. BÁRTEK. High speed of fork progression induces DNA replication stress and genomic instability. Nature. 2018, 559(7713), 279-284. ISSN 0028-0836. IF: 41.577. PMID: 29950726

BÜRGLOVÁ, K., G. RYLOVÁ, A. MARKOS, H. PŘICHYSTALOVÁ, M. SOURAL, M. PETRÁČEK, M. MEDVEDÍKOVÁ, G. TEJRAL, B. SOPKO, P. HRADIL, P. DŽUBÁK, M. HAJDÚCH a J. HLAVÁČ. Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1 H)-quinolinones as Novel Ligands with Anticancer Activity. Journal of Medicinal Chemistry. 2018, 61(7), 3027-3036. ISSN 0022-2623. IF: 6.259. PMID: 29498519

AGRAWAL, K., V. DAS, P. VYAS a M. HAJDÚCH. Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic. Pharmacology & Therapeutics. 2018, 188, 45-79. ISSN 0163-7258. IF: 11.127. PMID: 29454856

VANDA, D., M. SOURAL, V. CANALE, S. CHAUMONT-DUBEL, G. SATALA, T. KOS, P. FUNK, V. RUČILOVÁ, B. LEMROVÁ, K. P., E. PEKALA, A. BOJARSKI, P. POPIK, P. MARIN a P. ZAJDEL. Novel non-sulfonamide 5-HT6 receptor partial inverse agonist in a group of imidazo[4,5-b]pyridines with cognition enhancing properties. European Journal of Medicinal Chemistry. 2017, 144(2018), 716-729. ISSN 0223-5234. IF: 4.519. PMID: 29291439

ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199. ISSN 0028-0836. IF: 40.137. PMID: 29211715

MODER, M., G. VELIMEZI, M. OWUSU, A. MAZOUZI, M. WIEDNER, J. FERREIRA DA SILVA, L. ROBINSON-GARCIA, F. SCHISCHLIK, R. SLAVKOVSKÝ, R. KRALOVICS, B. SCHUSTER, C. BOCK, T. IDEKER, S. JACKSON, J. MENCHE a J. LOIZOU. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nature Communications. 2017, 8(1), 1238. ISSN 2041-1723. IF: 12.124. PMID: 29089570

EIGNEROVA, B., M. TICHÝ, J. KRASULOVA, L. RAROVA, R. CHRISTOVÁ, M. URBAN, B. BEDNARCZYK-CWYNAR, M. HAJDÚCH a J. ŠAREK. Q1_Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids. European Journal of Medicinal Chemistry. 2017, 140, 403-420. ISSN 0223-5234. IF: 4.519. PMID: 28987603

KARLÍKOVÁ, R., K. MIČOVÁ, L. NAJDEKR, A. GARDLO, T. ADAM, P. MAJEROVÁ, D. FRIEDECKÝ a A. KOVAC. Metabolic status of CSF distinguishes rats with tauopathy from controls. Alzheimer's Research & Therapy. 2017, 9(1), 78. ISSN 1758-9193. IF: 6.154. PMID: 28934963

VRZALIKOVA, K., M. IBRAHIM, M. VOCKERODT, T. PERRY, S. MARGIELEWSKA, L. LUPINO, E. NAGY, E. SOILLEUX, D. LIEBELT, R. HOLLOWS, A. LAST, G. REYNOLDS, M. ABDULLAH, H. CURLEY, M. CARE, D. KRAPPMANN, R. TOOZE, J. ALLEGOOD, S. SPIEGEL, W. WEI, C.B.J. WOODMAN a P. MURRAY. S1PR1 drives a feed forward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells. Leukemia. 2018, 32(1), 214-223. ISSN 0887-6924. IF: 11.702. PMID: 28878352

EFFENBERG, R., P. TURANEK KNOTIGOVA, D. ZYKA, H. CELECHOVSKA, J. MASEK, E. BARTHELDYOVA, F. HUBATKA, S. KOUDELKA, R. LUKAC, A. KOVALOVA, D. SAMAN, M. KŘUPKA, L. BARKOCZIOVA, P. KOSZTYU, M. ŠEBELA, L. DROZ, M. HUCKO, M. KANASKOVA, A.D. MILLER, M. RAŠKA, M. LEDVINA a J. TURANEK. Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo. Journal of Medicinal Chemistry. 2017, 60(18), 7745-7763. ISSN 0022-2623. IF: 6.259. PMID: 28829599

NARDONE, G., J. OLIVER-DE LA CRUZ, J. VRBSKY, C. MARTINI, J. PRIBYL, P. SKLADAL, M. PESL, G. CALUORI, S. PAGLIARI, F. MARTINO, Z. MACEČKOVÁ, M. HAJDÚCH, A. SANZ-GARCIA, N. PUGNO, G. STOKIN a G. FORTE. YAP regulates cell mechanics by controlling focal adhesion assembly. Nature Communications. 2017, 15, 8:15321. ISSN 2041-1723. IF: 11.329. PMID: 28504269

VAN GOOL, A., F. BIETRIX, E. CALDENHOVEN, K. ZATLOUKAL, A. SCHERER, J. LITTON, G. MEIJER, N. BLOMBERG, A. SMITH, B. MONS, J. HERINGA, W. KOOT, M. SMIT, M. HAJDÚCH, T. RIJNDERS a A.E. USSI. Bridging the translational innovation gap through good biomarker practice. Nature Reviews. Drug Discovery. 2017, 16(9), 587-588. ISSN 1474-1776 . IF: 57.000. PMID: 28450744

TICHÝ, M., S. SMOLEN, E. TLOUŠŤOVÁ, R. POHL, T. OŽDIAN, K. HEJTMÁNKOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides. Journal of Medicinal Chemistry. 2017, 60(6), 2411-2424. ISSN 0022-2623. IF: 5.589. PMID: 28221790

CHROMÁ, K., M. MISTRÍK, P. MOUDRÝ, J. GURSKÝ, M. LIPTAY, R. STRAUSS, Z. ŠKROTT, R. VRTEL, J. BARTKOVA, J. KRAMARA a J. BÁRTEK. Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress. Oncogene. 2017, 36(17), 2405-2422. ISSN 0950-9232 . IF: 7.932. PMID: 27841863

NAJDEKR, L., D. FRIEDECKÝ, R. TAUTENHAHN, T. PLUSKAL, J. WANG, Y. HUANG a T. ADAM. Influence of Mass Resolving Power in Orbital Ion-Trap Mass Spectrometry-Based Metabolomics. Analytical Chemistry. 2016, 88(23), 11429-11435. ISSN 0003-2700. IF: 6.320. PMID: 27809493

SKOLOUDIK, D., P. BARTOVA, J. MASKOVA, P. DUSEK, J. BLAHUTA, K. LANGOVÁ, D. WALTER a R. HERZIG. Transcranial Sonography of the Insula: Digitized Image Analysis of Fusion Images with Magnetic Resonance. Ultraschall in der Medizin . 2016, 37(6), 604-608. ISSN 0172-4614 . IF: 3.452. PMID: 27486795

JIRAVOVÁ, J., K. BARTOŇ TOMÁNKOVÁ, M. HARVANOVÁ, L. MALINA, J. MALOHLAVA, L. LUHOVA, A. PANACEK, B. MANIŠOVÁ a H. KOLÁŘOVÁ. The effect of silver nanoparticles and silver ions on mammalian and plant cells in vitro. Food and Chemical Toxicology. 2016, 96(-), 50-61. ISSN 0278-6915 . IF: 3.778. PMID: 27456126

BÜRGLOVÁ, K., S. OKOROCHENKOV a J. HLAVÁČ. Efficient Route to Deuterated Aromatics by the Deamination of Anilines. Organic Letters. 2016, 18(14), 3342-3345. ISSN 1523-7060. IF: 6.579. PMID: 27378277

GALANOS, P., K. VOUGAS, D. WALTER, A. POLYZOS, A. MAYA-MENDOZA, E. HAAGENSEN, A. KOKKALIS, F. ROUMELIOTI, S. GAGOS, M. TZETIS, B. CANOVAS, A. IGEA, A. AHUJA, R. ZELLWEGER, S. HAVAKI, E. KANAVAKIS, D. KLETSAS, I. RONINSON, S. GARBIS, M. LOPES, A. NEBREDA, D. THANOS, J. BLOW, P. TOWNSEND, C. SORENSEN, J. BÁRTEK a V. GOURGOULIS. Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing. Nature Cell Biology. 2016, 18(7), 777-789. ISSN 1465-7392 . IF: 20.060. PMID: 27323328

SMUTNY, T., A. NOVÁ, M. DRECHSLEROVA, A. CARAZO, L. HYRSOVA, Z. HRUSKOVA, J. KUNEŠ, M. POUR, M. SPULAK a P. PAVEK. 2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists. Journal of Medicinal Chemistry. 2016, 59(10), 4601-10. ISSN 0022-2623. IF: 6.259. PMID: 27145071

FOGLAROVA, M., J. CHMELAR, G. HUERTA-ANGELES, H. VAGNEROVA, J. KULHANEK, K. BARTOŇ TOMÁNKOVÁ, A. MINARIK a V. VELEBNY. Water-insoluble thin films from palmitoyl hyaluronan with tunable properties. Carbohydrate Polymers. 2016, 144, 68-75. ISSN 0144-8617. IF: 4.811. PMID: 27083794

GILLILAND, C.T., D. ZUK, P. KOCIS, M. JOHNSON, S. HAY, M. HAJDÚCH, F. BIETRIX, G. AVERSA, C.P. AUSTIN a A.E. USSI. Putting translational science on to a global stage. Nature Reviews Drug Discovery. 2016, 15, 217-219. ISSN 1474-1776. IF: 57.000. PMID: 27032820

MOUDRÝ, P., K. WATANABE, K. WOLANIN, J. BARTKOVA, I. WASSING, S. WATANABE, R. STRAUSS, R.S. PEDERSEN, V. OESTERGAARD, M. LISBY, M. ANDUJAR-SANCHEZ, A. MAYA-MENDOZA, F. ESASHI, J. LUKÁŠ a J. BÁRTEK. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. Journal of Cell Biology. 2016, 212(3), 281-288. ISSN 0021-9525 . IF: 7.955. PMID: 26811421

MISTRÍK, M., E. VESELÁ, T. FÜRST, H. HANZLIKOVA, I. FRYDRYCH, J. GURSKÝ, D. MAJERA a J. BÁRTEK. Cells and Stripes: A novel quantitative photo-manipulation technique. Scientific Reports. 2016, 6(-), Article Number: 19567. ISSN 2045-2322. IF: 4.259. PMID: 26777522

BRAUER, R., J. TURECKOVA, I. KANCHEV, M. KHOYLOU, J. ŠKARDA, J. PROCHAZKA, F. SPOUTIL, I.M. BECK, O. ŽBODÁKOVÁ, P. KASPAREK, V. KORINEK, K. CHALUPSKÝ, T. KARHU, K.H. HERZIG, M. HAJDÚCH, M. GREGOR a R. SEDLÁČEK. MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function. Mucosal Immunology. 2016, 9(4), 974-985. ISSN 1933-0219. IF: 7.478. PMID: 26555704

WU, T., J. KAPITAN, V. MAŠEK a P. BOUR. Detection of Circularly Polarized Luminescence of a Cs-EuIII Complex in Raman Optical Activity Experiments. Angewandte Chemie (International ed. in English). 2015, 54(49), 14933-6. ISSN 1433-7851 . IF: 11.709. PMID: 26473499

SURINOVA, S., M. CHOI, S. TAO, P.J. SCHÜFFLER, C.Y.. CHANG, T. CLOUGH, K. VYSLOUŽIL, M. KHOYLOU, J. SROVNAL, Y. LIU, M. MATONDO, R. HÜTTENHAIN, H. WEISSER, J.M. BUHMANN, M. HAJDÚCH, H. BRENNER, O. VITEK a R. AEBERSOLD. Prediction of colorectal cancer diagnosis based on circulating plasma proteins. EMBO Molecular Medicine. 2015, 7(9), 1166-1178. ISSN 1757-4676 . IF: 9.547. PMID: 26253081

SURINOVA, S., L. RADOVÁ, M. CHOI, J. SROVNAL, H. BRENNER, O. VITEK, M. HAJDÚCH a R. AEBERSOLD. Non-invasive prognostic protein biomarker signatures associated with colorectal cancer. EMBO Molecular Medicine. 2015, 7(9), 1153-1165. ISSN 1757-4676. IF: 9.547. PMID: 26253080

KOMIS, G., M. MISTRÍK, O. SAMAJOVA, M. OVECKA, J. BÁRTEK a J. SAMAJ. Superresolution live imaging of plant cells using structured illumination microscopy. Nature Protocols. 2015, 10(8), 1248-1263. ISSN 1754-2189. IF: 9.646. PMID: 26203822

DIETLEIN, F., B. KALB, M. JOKIC, E. NOLL, A. STRONG, L. THARUN, L. OZRETIC, H. KUNSTLINGER, K. KAMBARTEL, W. RANDERATH, C. JUNGST, A. SCHMITT, A. TORGOVNICK, A. RICHTERS, D. RAUH, F. SIEDEK, T. PERSIGEHL, C. MAUCH, J. BARTKOVA, A. BRADLEY, M. SPRICK, A. TRUMPP, R. RAD, D. SAUR, J. BÁRTEK, J. WOLF, R. BUTTNER, R. THOMAS a H. REINHARDT. A Synergistic Interaction between Chk1-and MK2 Inhibitors in KRAS-Mutant Cancer. Cell. 2015, 162(1), 146-159. ISSN 0092-8674. IF: 28.710. PMID: 26140595

FORMARA, O., J.J. BARTEK, A. RAHBAR, J. ODEBERG, Z. KHAN, I. PEREDO, P. HAMERLIK, J. BÁRTEK, G. STRAGLIOTTO, N. LANDAZURI a C. SODERBERG-NAUCLER. Cytomegalovirus infection induces a stem cell phenotype in human primary glioblastoma cells: prognostic significance and biological impact. Cell Death and Differentiation. 2016, 23(2), 261-269. ISSN 1350-9047. IF: 8.339. PMID: 26138445

KVASNICA, M., M. URBAN, N.J. DICKINSON a J. ŠAREK. Pentacyclic triterpenoids with nitrogen- and sulfur-containing heterocycles: synthesis and medicinal significance. Natural Product Reports. 2015, 20(32), 1303-1330. ISSN 0265-0568. IF: 10.986. PMID: 26030604

ZHAI, C., D. SUMMER, C. RANGGER, G. FRANSSEN, P. LAVERMAN, H. HAAS, M. PETŘÍK, R. HAUBNER a C. DECRISTOFORO. Novel Bifunctional Cyclic Chelator for (89)Zr Labeling-Radiolabeling and Targeting Properties of RGD Conjugates. Molecular Pharmaceutics. 2015, 12(6), 2142-2150. ISSN 1543-8384. IF: 4.342. PMID: 25941834

DAS, V., F. BRUZZESE, P. KONEČNÝ, F. IANNELLI, A. BUDILLON a M. HAJDÚCH. Pathophysiologically relevant in vitro tumor models for drug screening. Drug Discovery Today. 2015, 20(7), 848-55. ISSN 1359-6446. IF: 5.625. PMID: 25908576

XU, G., J. CHAPMAN, I. BRANDSMA, J. YUAN, M. MISTRÍK, P. BOUWMAN, J. BARTKOVA, E. GOGOLA, D. WARMERDAM, M. BAZARAS, J. JASPERS, K. WATANABE, M. PIETERSE, K. KERSBERGEN, W. SOL, P. CELIE, P. SCHOUTEN, B. VAN DEN BROEK, A. SALMAN, M. NIEUWLAND, I. DE RINK, J. DE RONDE, K. JALINK, S. BOULTON, J. CHEN, D. VAN GENT, J. BÁRTEK, J. JONKERS, P. BORST a S. ROTTENBERG. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015, 521(7553), 541-544. ISSN 0028-0836. IF: 38.138. PMID: 25799992

KANU, N., E. GRONROOS, P.. MARTINEZ, R.A. BURRELL, X.Y. GOH, J. BARTKOVA, A. MAYA-MENDOZA, M. MISTRÍK, A.J. ROWAN, H. PATEL, A. RABINOWITZ, P. EAST, G. WILSON, C.R. SANTOS, N. MCGRANAHAN, S. GULATI, M. GERLINGER, N.J. BIRKBAK, T. JOSHI, L.B. ALEXANDROV, M.R. STRATTON, T. POWLES, N. MATTHEWS, P.A. BATES, A. STEWART, Z. SZALLASI, J. LARKIN, J. BÁRTEK a C. SWANTON. SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. Oncogene. 2015, 34(46), 5699-5708. ISSN 0950-9232. IF: 7.932. PMID: 25728682

DAS, V., J. DVOŘANOVÁ ŠTĚPÁNKOVÁ, M. HAJDÚCH a J.H. MILLER. Role of tumor hypoxia in acquisition of resistance to microtubule-stabilizing drugs. Biochimica et Biophysica Acta Reviews on Cancer. 2015, 1855(2), 172-182. ISSN 0304-419X. IF: 7.841. PMID: 25662312

HAAS, H., M. PETŘÍK a C. DECRISTOFORO. An iron-mimicking Trojan horse entering fungi - has the time come for molecular imaging of fungal infections?. PLOS Pathogens. 2015, 11(1), 1-7. ISSN 1553-7366. IF: 7.003. PMID: 25634225

OKOROCHENKOV, S., K. BÜRGLOVÁ, I. POPA a J. HLAVÁČ. Solid-Supported Hydrazone of 4-(4 '-Formyl-3 '-methoxyphenoxy)butyric Acid As a New Traceless Linker for Solid-Phase Synthesis. Organic Letters. 2015, 17(2), 180-183. ISSN 1523-7060. IF: 6.732. PMID: 25536078

KULIHA, M., M. ROUBEC, V. PROCHAZKA, T. JONSZTA, T. HRBAC, J. HAVELKA, A. GOLDIROVA, K. LANGOVÁ, R. HERZIG a D. SKOLOUDIK. Randomized clinical trial comparing neurological outcomes after carotid endarterectomy or stenting. British Journal of Surgery. 2015, 102(3), 194-201. ISSN 0007-1323. IF: 5.596. PMID: 25511816

CHRISTENSEN, C., J. BARTKOVA, M. MISTRÍK, A. HALL., M.K. LANGE, U. RALFKIÆR, J. BÁRTEK a P. GULDBERG. A short acidic motif in ARF guards against mitochondrial dysfunction and melanoma susceptibility. Nature Communications. 2014, 5(5348), -. ISSN 2041-1723. IF: 11.470. PMID: 25370744

SNÁŠEL, J., P. NAUŠ, J. DOSTÁL, A. HNÍZDA, J. FANFRLÍK, J. BRYNDA, A. BOURDERIOUX, M. DUŠEK, H. DVOŘÁKOVÁ, J. STOLAŘÍKOVÁ, H. ZÁBRANSKÁ, R. POHL, P. KONEČNÝ, P. DŽUBÁK, I. VOTRUBA, M. HAJDÚCH, P. ŘEZÁČOVÁ, V. VEVERKA, M. HOCEK a I. PICHOVÁ. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry. 2014, 57(20), 8268-8279. ISSN 0022-2623. IF: 5.447. PMID: 25259627

BLASIUS, M., S.A. WAGNER, C. CHOUDHARY, J. BÁRTEK a S.P. JACKSON. A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response. Genes & Development. 2014, 28(18), 1977-1982. ISSN 0890-9369. IF: 10.798. PMID: 25189701

KISSELJOVA, K., P. SMYSLOVÁ a V. KRCHŇÁK. Benzhydrylamines via Base-Mediated Intramolecular sp(3) C-Arylation of N-Benzyl-2-nitrobenzenesulfonamides-Advanced Intermediates for the Synthesis of Nitrogenous Heterocycles. ACS Combinatorial Science. 2014, 16(10), 573-577. ISSN 2156-8952. IF: 3.032. PMID: 25180543

OKA, Y., H. VARMARK, K. VITTING-SEERUP, P. BELI, J. WAAGE, A. HAKOBYAN, M. MISTRÍK, C. CHOUDHARY, M. ROHDE, S. BEKKER-JENSEN a N. MAILAND. UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells. EMBO Reports. 2014, 15(9), 956-964. ISSN 1469-221X. IF: 9.055. PMID: 25092792

KUMAR, A., M. MAZZANTI, M. MISTRÍK, M. KOSAR, G.V. BEZNOUSSENKO, A.A. MIRONOV, M. GARRE, D. PARAZZOLI, G. SHIVASHANKAR, G. SCITA, J. BÁRTEK a M. FOIANI. ATR Mediates a Checkpoint at the Nuclear Envelope in Response to Mechanical Stress. Cell. 2014, 158(3), 633-646. ISSN 0092-8674. IF: 32.242. PMID: 25083873

SMYSLOVÁ, P., K. KISSELJOVA a V. KRCHŇÁK. Base-Mediated Intramolecular C- and N-Arylation of N,N-Disubstituted 2-Nitrobenzenesulfonamides: Advanced Intermediates for the Synthesis of Diverse Nitrogenous Heterocycles. ACS Combinatorial Science. 2014, 16(9), 500-505. ISSN 2156-8952. IF: 3.032. PMID: 25076047

LEMROVÁ, B., P. SMYSLOVÁ, I. POPA, T. OŽDIAN, P. ZAJDEL a M. SOURAL. Directed Solid-Phase Synthesis of Trisubstituted Imidazo[4,5-c]pyridines and Imidazo[4,5-b]pyridines. ACS Combinatorial Science. 2014, 16(10), 558-565. ISSN 2156-8952. IF: 3.032. PMID: 25046560

FÜLÖPOVÁ, V. a V. KRCHŇÁK. Solid-Phase Synthesis of Trisubstituted 2,5-Dihydrobenzo[f][1,2,5]thiadiazepine 1,1-Dioxide Derivatives. ACS Combinatorial Science. 2014, 16(8), 412-420. ISSN 2156-8952. IF: 3.032. PMID: 24884092

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MCMASTER, C., V. FÜLÖPOVÁ, I. POPA, M. GREPL a M. SOURAL. Solid-Phase Synthesis of Anagrelide Sulfonyl Analogues. ACS Combinatorial Science. 2014, 16(5), 221-224. ISSN 2156-8952. IF: 3.032. PMID: 24725158

VENTOSA-ANDRÉS, P., L. HRADILOVÁ a V. KRCHŇÁK. Privileged Structures as Peptide Backbone Constraints: Polymer-Supported Stereoselective Synthesis of Benzimidazolinopiperazinone Peptides. ACS Combinatorial Science. 2014, 16(7), 359-366. ISSN 2156-8952. IF: 3.032. PMID: 24725105

KOMIS, G., M. MISTRÍK, O. SAMAJOVA, A. DOSKOCILOVA, M. OVECKA, P. ILLES, J. BÁRTEK a J. SAMAJ. Dynamics and Organization of Cortical Microtubules as Revealed by Superresolution Structured Illumination Microscopy. Plant Physiology. 2014, 165(1), 129-148. ISSN 0032-0889. IF: 6.841. PMID: 24686112

CANKAŘOVÁ, N., A.L. VENIA a V. KRCHŇÁK. Polymer-Supported Stereoselective Synthesis of Tetrahydrobenzopyrazino-thiadiazinone Dioxides via N-Sulfonyl Iminiums. ACS Combinatorial Science. 2014, 16(6), 293-302. ISSN 2156-8952. IF: 3.032. PMID: 24575715

BURRELL, R.A., S.E. MCCLELLAND, J. BÁRTEK a C. SWANTON. Response to Bakhoum et al. Current Biology. 2014, 24(4), R150-R150. ISSN 0960-9822. IF: 9.571. PMID: 24556434

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BHATTACHARYYA, T., R. REIFOVA, S. GREGOROVA, P. SIMECEK, V. GERGELITS, M. MISTRÍK, I. MARTINCOVA, J. PIALEK a J. FOREJT. X Chromosome Control of Meiotic Chromosome Synapsis in Mouse Inter-Subspecific Hybrids. PLOS Genetics. 2014, 10(2), -. ISSN 1553-7404. IF: 7.528. PMID: 24516397

FOIANI, M. a J. BÁRTEK. Golgi Feels DNA's Pain. Cell. 2014, 156(3), 392-393. ISSN 0092-8674. IF: 32.242. PMID: 24485446

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MESSINA, I., I. POPA, V. MAIER a M. SOURAL. Solid-Phase Synthesis of 5-Noranagrelide Derivatives. ACS Combinatorial Science. 2014, 16(1), 33-38. ISSN 2156-8952. IF: 3.032. PMID: 24304422

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WATANABE, S., K. WATANABE, V. AKIMOV, J. BARTKOVA, B. BLAGOEV, J. LUKÁŠ a J. BÁRTEK. JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks. Nature Structural & Molecular Biology. 2013, 20(12), 1425-1433. ISSN 1545-9993. IF: 11.633. PMID: 24240613

YAMADA, M., K. WATANABE, M. MISTRÍK, E. VESELÁ, I. PROTIVÁNKOVÁ, N. MAILAND, M. LEE, H. MASAI, J. LUKÁŠ a J. BÁRTEK. ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress. Genes & Development. 2013, 27(22), 2459-2472. ISSN 0890-9369. IF: 12.639. PMID: 24240236

BÁRTEK, J., M. MISTRÍK a J. BARTKOVA. Androgen receptor signaling fuels DNA repair and radioresistance in prostate cancer. Cancer Discovery. 2013, 3(11), 1222-1224. ISSN 2159-8274. IF: 15.929. PMID: 24203954

ALTMEYER, M., L. TOLEDO, T. GUDJONSSON, M. GROFTE, M.B. RASK, C. LUKAS, V. AKIMOV, B. BLAGOEV, J. BÁRTEK a J. LUKÁŠ. The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling. Molecular Cell. 2013, 52(2), 1097-2765. ISSN 1097-2765. IF: 14.464. PMID: 24055346

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SKOLOUDIK, D., M. KULIHA, M. ROUBEC, T. JONSZTA, V. PROCHAZKA, K. LANGOVÁ a R. HERZIG. Safety and Efficacy of Endovascular Sonolysis Using the EkoSonic Endovascular System in Patients with Acute Stroke. American Journal of Neuroradiology. 2013, 34(7), 1401-1406. ISSN 0195-6108. IF: 3.675. PMID: 23370469

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VRBA, J., R. GAZAK, M. KUZMA, B. PAPOUSKOVA, J. VACEK, M. WEISZENSTEIN, V. KREN a J. ULRICHOVÁ. A Novel Semisynthetic Flavonoid 7‑O‑Galloyltaxifolin Upregulates Heme Oxygenase‑1 in RAW264.7 Cells via MAPK/Nrf2 Pathway. Journal of Medicinal Chemistry. 2013, 56(3), 856-866. ISSN 0022-2623. IF: 5.480. PMID: 23294286

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FALCK, J., J. FORMENT, J. COATES, M. MISTRÍK, J. LUKÁŠ, J. BÁRTEK a S.P. JACKSON. CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination. EMBO Reports. 2012, 13(6), 561-568. ISSN 1469-221X. IF: 7.189. PMID: 22565321

PETŘÍK, M., G. FRANSSEN, H. HAAS, P. LAVERMAN, C. HÖRTNAGL, M. SCHRETTL, A. HELBOK, C. LASS-FLÖRL a C. DECRISTOFORO. Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging. European Journal of Nuclear Medicine and Molecular Imaging. 2012, 39(7), 1175-1183. ISSN 1619-7070. IF: 5.114. PMID: 22526953

TAKACOVA, S., R. SLANY, J. BARTKOVA, V. STRANECKY, P. DOLEZEL, P. LUŽNÁ, J. BÁRTEK a V. DIVOKÝ. Damage Response and Inflammatory Signaling Limit the MLL-ENL-Induced Leukemogenesis In Vivo. Cancer Cell. 2012, 21(4), 517-531. ISSN 1535-6108. IF: 24.755. PMID: 22516260

BARTEK, J.J., K. NG, J. BÁRTEK, W. FISCHER, B. CARTER a C.C. CHEN. Key concepts in glioblastoma therapy. Journal of Neurology Neurosurgery and Psychiatry. 2012, 83(7), 753-760. ISSN 0022-3050. IF: 4.924. PMID: 22396442

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STRAUSS, R., P. HAMERLIK, A. LIEBER a J. BÁRTEK. Regulation of Stem Cell Plasticity: Mechanisms and Relevance to Tissue Biology and Cancer. Molecular Therapy. 2012, 20(5), 887-897. ISSN 1525-0016. IF: 7.041. PMID: 22314288

BÁRTEK, J., M. MISTRÍK a J. BARTKOVA. Thresholds of replication stress signaling in cancer development and treatment. Nature Structural & Molecular Biology. 2012, 19(1), 5-7. ISSN 1545-9993. IF: 11.902. PMID: 22218289

JANEČKOVÁ, H., K. HRON, P. WOJTOWICZ, E. HLIDKOVA, A. BARESOVA, D. FRIEDECKÝ, L. ŽÍDKOVÁ, P. HORNIK, D. BEHULOVA, D. PROCHAZKOVA, H. VINOHRADSKA, K. PESKOVA, P. BRUHEIM, V. SMOLKA, S. STASTNA a T. ADAM. Targeted metabolomic analysis of plasma samples for the diagnosis of inherited metabolic disorders. Journal of Chromatography A. 2012, 1226(-), 11-17. ISSN 1873-3778. IF: 4.612. PMID: 22018716

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SERIO, G., V. MARGARIA, S. JENSEN, A. OLDANI, J. BÁRTEK, F. BUSSOLINO a L. LANZETTI. Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores. Proceedings of the National Academy of Sciences of the United States of America. 2011, 108(42), 17337-17342. ISSN 0027-8424. IF: 9.681. PMID: 21987812

LUKÁŠ, J., C. LUKAS a J. BÁRTEK. More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance. Nature Cell Biology. 2011, 13(10), 1161-1169. ISSN 1465-7392. IF: 19.488. PMID: 21968989

LUKÁŠ, J. a J. BÁRTEK. Tethered Genes Get Checked during Replication. Cell. 2011, 146(2), 189-191. ISSN 0092-8674. IF: 32.403. PMID: 21784241

BOURDERIOUX, A., P. NAUŠ, P. PERLÍKOVÁ, R. POHL, I. PICHOVÁ, I. VOTRUBA, P. DŽUBÁK, P. KONEČNÝ, M. HAJDÚCH, K.M. STRAY, T. WANG, A.S. RAY, J.Y. FENG, G. BIRKUS, T. CIHLÁŘ a M. HOCEK. Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines. Journal of Medicinal Chemistry. 2011, 54(15), 5498-5507. ISSN 0022-2623. IF: 5.248. PMID: 21711054

BÁRTEK, J. a J. LUKÁŠ. DNA REPAIR Cyclin D1 multitasks. Nature. 2011, 474(7350), 171-172. ISSN 0028-0836. IF: 36.280. PMID: 21654798

KRIEGOVA, E., R. FILLEROVA, T. TOMANKOVA, B. HUTYROVA, F. MRÁZEK, T. TICHÝ, V. KOLEK, R.M. DU BOIS a M. PETŘEK. T-helper cell type-1 transcription factor T-bet is upregulated in pulmonary sarcoidosis. European Respiratory Journal. 2011, 38(5), 1136-1144. ISSN 0903-1936. IF: 5.895. PMID: 21540308

JORDA, R., L. HAVLICEK, I.W. MCNAE, M.D. WALKINSHAW, J. VOLLER, A. STURC, J. NAVRATILOVA, M. KUZMA, M. MISTRÍK, J. BÁRTEK, M. STRNAD a V. KRYŠTOF. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity. Journal of Medicinal Chemistry. 2011, 54(8), 2980-2993. ISSN 0022-2623. IF: 5.248. PMID: 21417417

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LÖFFLER, H., A. FECHTER, M. MATUSZEWSKA, R. SAFFRICH, M. MISTRÍK, J. MARHOLD, C. HORNUNG, F. WESTERMANN, J. BÁRTEK a A. KRÄMER. Cep63 Recruits Cdk1 to the Centrosome: Implications for Regulation of Mitotic Entry, Centrosome Amplification, and Genome Maintenance. Cancer Research. 2011, 71(6), 2129-2139. ISSN 0008-5472. IF: 7.856. PMID: 21406398

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WOJTOWICZ, P., J. ZROSTLÍKOVÁ, T. KOVALCZUK, J. SCHUREK a T. ADAM. Evaluation of comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry for the diagnosis of inherited metabolic disorders using an automated data processing strategy. Journal of Chromatography A. 2010, 1217(51), 8054-8061. ISSN 0021-9673. IF: 4.194. PMID: 20961553

BÁRTEK, J., M. MISTRÍK a J. BARTKOVA. Long-distance inflammatory and genotoxic impact of cancer in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2010, 107(42), 17861-17862. ISSN 0027-8424. IF: 9.771. PMID: 20926747

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KOSINA, P., A. DOKOUPILOVA, K. JANDA, K. SLADKOVA, P. SILBEROVA, V. PIVODOVÁ a J. ULRICHOVÁ. Effect of Silybum marianum fruit constituents on the healthstatus of rabbits in repeated 42-day fattening experiment. Animal Feed Science and Technology. 2017, 223(2017), 128-140. ISSN 0377-8401. IF: 2.143.

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SCHUTZNEROVA, E., A. OLIVER, A. PRIBYLKA a V. KRCHŇÁK. Solid-Phase Synthesis of Tetramic Acid via Resin-Bound Enol Ethers as a Privileged Scaffold in Drug Discovery. Advanced Synthesis and catalysis. 2018, 360(19), 3693-3699. ISSN 1615-4150. IF: 5.123.