Das Viswanath M.Sc., Ph.D.

Journals

DAS, V., L. DIOMEDE, L. MALINA, M. MOSCONI, N. ANNADURAI
Intrinsic aggregation and propagation of unmodified tau peptides: R2R3 as a minimal model system. Biophysical Journal. 2025, ISSN: 0006-3495 , PMID: 40515399,
DEVIATOV, A., I. KOZLOV, V. DAS
Differentiation of SH-SY5Y Cells into Cortical Neuron-like Cells for Tauopathy Modeling and Seeding Assays. Molecular Neurobiology. 2025, ISSN: 0893-7648, PMID: 40467940,  PDF.
RAMPEESA, N., R. GUNDLA, G. MUDASANI, S. TANGALLAPALLI, S. ANUGU, S. GURSKÁ, J. DE SANCTIS, P. DŽUBÁK, M. HAJDÚCH, V. DAS
Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity. Bioorganic Chemistry. 2025, 157, 108316, ISSN: 0045-2068, PMID: 40037026,  PDF.

Books & book chapters

DAS, V.
Multiparametric analysis of spheroid integrity by brightfield high-content microscopy , 1.vyd., Olomouc, Palacky University, 2021, 24, 177-182, Dedication: LO1304, ISBN: 978-80-244-6049-9,
DAS, V.
Cell lines and cell culture conditions - 3D cultures , 1.vyd., Olomouc, Palacky University, 2021, 2, 15, Dedication: LO1304, ISBN: 978-80-244-6049-9,
ANNADURAI, N., V. DAS
A combination of kinetic fluorometric assay and microscopy for the screening of potential anti-tau aggregating agents, 1.vyd., Olomouc, Palacky University, 2021, 41, 317-324, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Doctoral mentorship

Annadurai Narendran M.Sc., Ph.D.

Identification and Characterisation of Tau minimal regions as Potential Pharmacological Targets against Tau Spreading in Tauopathies

Status: Graduated from 2015 to 2023.
Kozlov Ihor

Role of axonal transport and pathology in neurodegeneration

Status: Ongoing from 2023.

Master mentorship

Bechná Eliška

3D spheroids cultures of tumor cell lines for drug discovery studies

Status: Ongoing from 2022.
Pavlíková Martina

Specific pharmacological modulators of tau aggregation and spreading for Alzheimer's disease preclinical studies.

Status: Graduated from 2022 to 2024.
Skoupilová Patricie

Examination of mutations in tau on the activity of small molecules against prion-like tau formation in tauopathies

Status: Ongoing from 2023.

Bachelor mentorship

Chudáčková Alica

Investigating the biochemical and structural alterations in tau mutants caused by VQIVYK-targeting tau inhibitors

Status: Ongoing from 2023.
Vrablíková Barbora

Cytotoxicity of microtubule-stabilizing drug laulimalide in hypoxic human colorectal and cervical cancer cells

Status: Graduated from 2018 to 2020.

Open positions

Project: The role of tumor hypoxia in the emergence of acquired resistance to drugs aimed at microtubules
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Role of axonal transport and pathology in neurodegeneration
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Systems approaches to understanding aging and neurodegeneration
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Mitochondrial and microglial dysfunction in tauopathies: effects of pathogenic TAU strains
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Investigating Effects of Aggregates of Intrinsically Disordered Proteins on Microglia: Implication for Neurodegenerative Diseases
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Master training
Summary: -
Project: Biochemical and cellular analysis of amyloid staining agents in models of tauopathies and synucleopathies
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Master training
Summary: -
Project: Generation of 3D human neuronal cultures: application to modeling CNS diseases
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Master training
Summary: -
Project: Efficacy of Bruton Tyrosine Kinase Inhibitors Against Neuroinflammation in Neurodegenerative Diseases
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Master training
Summary: -