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Džubák Petr M.D., Ph.D.

Journals

FLEUTI, M., T. SANCHEZ-QUIRANTE, L. POSTOVA SLAVETINSKA, E. TLOUŠŤOVÁ, M. TICHÝ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, M. HOCEK
Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides. ACS Omega. 2024, 9(18), 20557-20570, ISSN: 2470-1343, PMID: 38737052,  PDF.
Pooling of samples to optimise SARS-CoV-2 detection in nasopharyngeal swabs and gargle lavage self-samples for covid-19 diagnostics and surveillance. Infectious Diseases. 2024, 1-12, ISSN: 2374-4243, PMID: 38549542.
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action. European Journal of Medicinal Chemistry. 2024, 269, 116336, ISSN: 0223-5234, PMID: 38520761,  PDF.

Intellectual property

SUBSTITUTED 7-DEZAPURIN RIBONUCLEOSIDES (Hocek)
  1. Patent: CZ 305466. Granted: 7.9.2015. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK PetrHAJDÚCH Marián 
  2. Patent: JP 5485172. Granted: 7.5.2014. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK PetrHAJDÚCH Marián 
  3. Patent: US 9,586,986. Granted: 7.3.2017. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK PetrHAJDÚCH Marián
  4. Patent: AU 20142777740. Granted: 25.2.2016. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK PetrHAJDÚCH Marián

Status: Available

BENZOISOTHIAZOLE-1, 1-DIOXIDE-3-HYDRAZONES AND THEIR USE IN ANTICANCER THERAPY (Kaplánek)
  1. Patent: CZ 306554. Granted: 25.1 2017. Ownership: Institute of Chemical Technology Prague; Palacký University Olomouc; Institute of Molecular Genetics CAS. Inventors: KAPLÁNEK Robert, BŘÍZA Tomáš, HAVLÍK Martin, RAK Jakub, KEJÍK Zdeněk, DŽUBÁK PetrHAJDÚCH Marián, KONEČNÝ Petr, ŠTĚPÁNKOVÁ Jana, KRÁLOVÁ Jarmila, KRÁL Vladimír

​Status: Terminated

DIOXOCYCLOBUTENYL HYDRAZONES AND THEIR ANTICANCER ACTIVITY (Kaplánek)
  1. Patent: CZ 305626. Granted: 2.12.2015. Ownership: Institute of Chemical Technology Prague; Palacký University Olomouc; Institute of Molecular Genetics CAS. Inventors: KAPLÁNEK Robert, BŘÍZA Tomáš, HAVLÍK Martin, RAK Jakub, KEJÍK Zdeněk, DŽUBÁK PetrHAJDÚCH Marián, KONEČNÝ Petr, ŠTĚPÁNKOVÁ Jana, KRÁLOVÁ Jarmila, KRÁL Vladimír

​Status: Terminated

Doctoral mentorship

Heffnerová Ema

Identification of molecular targets and mechanisms of resistance in anticancer drugs by cell biology methods and proteomics

Status: Ongoing from 2024.
Bartáková Anna

Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease

Status: Ongoing from 2024.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of new derivatives targeting precancerous and tumor lesions and their mechanisms of action
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training