Pokorný Jan Ph.D.

Journals

BACHOŘÍK, J., I. FRYDRYCH, S. GURSKÁ, S. DOSTAL, J. POKORNÝ, M. HAJDÚCH, M. URBAN
New Synthetic Approach to C‑30 Ethers, Esters, and Amines of Betulin Using the Mitsunobu Reaction and Biological Evaluation of the Products. ACS Omega. 2026, 11(16), 24564-24579, ISSN: 2470-1343, PMID: 42077890,  PDF.
FRYDRYCH, I., J. ŘEHULKA, L. SLAVIKOVA, J. HODOŇ, J. HODOŇ, J. POKORNÝ, V. ŠIDOVÁ, M. MEDVEDÍKOVÁ, H. SLAVÍK, P. POLISHCHUK, T. OŽDIAN, J. VRBKOVÁ, J. ŠAREK, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Triterpenoid derivatives inhibit Gli-mediated transcription in human glioblastoma cell line via direct interaction with Gli1. The Journal of biological chemistry. 2025, ISSN: 0021-9258, PMID: 40651614,  PDF.
FRYDRYCH, I., B. CHROMA, L. SLAVIKOVA, J. POKORNÝ, N. JAKUBCOVÁ, S. LUDHA, S. GURSKÁ, J. ŘEHULKA, B. LIŠKOVÁ, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Novel C-2 Aromatic Heterocycle-Substituted Triterpenoids Inhibit Hedgehog Signaling in GLI1 Overexpression Cancer Cells. ACS Omega. 2025, 10(10), 10617-10632, ISSN: 2470-1343, PMID: 40124057,  PDF.

Master mentorship

Wardasová Nela

A-ring modification of betulinic acid

Status: Ongoing from 2025.