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Telefon: +420 585634855
Skupiny: IMTM, LEM, PERSONÁL

O mně

Positions:
researcher (drug screening, bio-/cheminformatician)
Institute of Molecular and Translational Medicine, Faculty of Medicine & Dentistry, Palacky University
since 2011

researcher (biology of stress and aging)
Department of Experimental Biology, Faculty of Science, Palacký University
since 2022

researcher (biology of stress and aging)
Laboratory of Growth Regulators, Institute of Experimental Botany AS CR & Palacký University
2010-2022

Education:
Palacký University, Faculty of Science, Olomouc, Czech Republic
PhD - biology

Charles University - Pharmaceutical Faculty, Hradec Králové - Czech Republic
MSc - pharmacy
 

Masaryk University, Faculty of Science, Brno, Czech Republic
MSc - molecular biology/genetics



Research Interests:
- biology of stress and aging (human cells, C. elegans, water bears)
- circadian rhythms
- drug screening ( circadian rhythm modulators, cytoprotection,  mitochondrial diseases,  parasitic worms,  ...)
- bio- and cheminformatics (identification of mechanism of drug action, comparison of drugs based on biological activity profiles, image analysis, machine learning)

Teaching:
Biogerontology
Drug Discovery
Biology of Circadian Rhythms and Sleep
Biology of Reproduction
 

Journals

ISKAUSKIENE, M., A. KADLECOVA, J. VOLLER, L. JANOVSKA, V. MALINAUSKIENE, A. ZUKAUSKAITE, A. SACKUS
Synthesis of 5-[(1H-indol-3-yl)methyl]-1,3,4-oxadiazole-2(3H)-thiones and their protective activity against oxidative stress. Archiv der Pharmazie. 2021, 54(6), e2100001, ISSN: 0365-6233, PMID: 33733468,
MAKOVA, B., V. MIK, B. LIŠKOVÁ, G. GONZALES, D. VÍTEK, M. MEDVEDÍKOVÁ, B. MONFORT, V. RUČILOVÁ, A. KADLECOVA, P. KHIRSARIYA, Z. BARREIRO, L. HAVLICEK, M. ZATLOUKAL, M. SOURAL, K. PARUCH, B. D´AUTREAUX, M. HAJDÚCH, M. STRNAD, J. VOLLER
Cytoprotective activities of kinetin purine isosteres. Bioorganic & Medicinal Chemistry. 2021, 1(33), 115993, ISSN: 0968-0896, PMID: 33497938,
KADLECOVA, A., B. MAKOVA, M. ARTAL-SANZ, M. STRNAD, J. VOLLER
The plant hormone kinetin in disease therapy and healthy aging. Ageing Rsearch Reviews. 2019, 55, 100958, ISSN: 1568-1637, PMID: 31479763,

Volná místa

1 Molekulární a buněčná biologie
Projekt: Search and characterization of substances for the therapy of congenital or acquired diseases caused by aberrant pre-mRNA splicing
Vedoucí: Voller Jiří Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční formě studia
1 Chemická biologie a experimentální terapie
Projekt: Search and study of the mechanism of action of substances affecting the viability and motility of human spermatozoa
Vedoucí: Voller Jiří Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční formě studia
2 Molekulární a translační medicína
Projekt: Physiology and pathophysiology of aging
Vedoucí: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 místa v prezenční formě studia
Projekt: Search and study of the mechanism of action of new modulators of circadian rhythms for the therapy of civilization diseases
Vedoucí: Voller Jiří Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční formě studia