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Telefon: +420 585634855
Skupiny: IMTM, LEM, PERSONÁL

O mně

Positions:
researcher (drug screening, bio-/cheminformatician)
Institute of Molecular and Translational Medicine, Faculty of Medicine & Dentistry, Palacky University
since 2011

researcher (biology of stress and aging)
Department of Experimental Biology, Faculty of Science, Palacký University
since 2022

researcher (biology of stress and aging)
Laboratory of Growth Regulators, Institute of Experimental Botany AS CR & Palacký University
2010-2022

Education:
Palacký University, Faculty of Science, Olomouc, Czech Republic
PhD - biology

Charles University - Pharmaceutical Faculty, Hradec Králové - Czech Republic
MSc - pharmacy
 

Masaryk University, Faculty of Science, Brno, Czech Republic
MSc - molecular biology/genetics



Research Interests:
- biology of stress and aging (human cells, C. elegans, water bears)
- circadian rhythms
- drug screening ( circadian rhythm modulators, cytoprotection,  mitochondrial diseases,  parasitic worms,  ...)
- bio- and cheminformatics (identification of mechanism of drug action, comparison of drugs based on biological activity profiles, image analysis, machine learning)

Teaching:
Biogerontology
Drug Discovery
Biology of Circadian Rhythms and Sleep
Biology of Reproduction
 

Journals

KADLECOVA, A., K. DZEDULIONYTE MÜLDÜR, M. PERINA, K. BIELESZOVA, C. ZHANG, D. KOVÁŘÍČEK, E. VALDERAS-GARCIA, D. VÍTEK, M. VALIKONYTE, A. SACKUS, J. SOLOVJOVA, V. MALINAUSKIENE, K. DOLEZAL, O. NOVAK, F. GRUNDLER, P. ROY, M. MARTINEZ-VALLADARES, J. VOLLER, A. SCHLEKER
Synthesis, Anthelmintic Activity, and Mechanism of Action of 5-Aryl-1 H-indoles. Journal of Agricultural and Food Chemistry. 2025, ISSN: 0021-8561 , PMID: 41401077,
MAKOVA, B., V. MIK, B. LIŠKOVÁ, L. DRASAROVA, M. MEDVEDÍKOVÁ, A. HORINKOVA, P. VOJTA, M. ZATLOUKAL, L. PLÍHALOVÁ, M. HONIG, K. DOLEZAL, K. FOREJT, T. OŽDIAN, M. HAJDÚCH, M. STRNAD, J. VOLLER
Correction of aberrant splicing of ELP1 pre-mRNA by kinetin derivatives - A structure activity relationship study. European Journal of Medicinal Chemistry. 2024, ISSN: 0223-5234, PMID: 39756144,  PDF.
SUSHOVAN, J., G. GONZALES, D. VÍTEK, M. KVASNICOVA, S. STEPANKOVA, M. STRNAD, J. VOLLER, K. CHANDA
Novel neuroprotective 5,6-dihydropyrido[2',1':2,3]imidazo[4,5-c]quinoline derivatives acting through cholinesterase inhibition and CB2 signaling modulation. European Journal of Medicinal Chemistry. 2024, 276, 116592, ISSN: 0223-5234, PMID: 39013357,  PDF.

Intellectual property

HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND THERAPY OF CIRCADIAN RHYTHM DISORDERS - PV 2022-227 (Voller)
  1. Published Application: PCT/CZ2023/050029 under WO 2023/232171 (7.12.2023)
  2. Published Application US 18/868,011 under US 2025346601 (13.11.2025)
  3. Patent: EP 4532498. Granted: 29.10.2025. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, MIK Václav, DOKONALOVÁ Markéta, SLÁDEK Martin, SUMOVÁ Alena, HAJDÚCH Marián, STRNAD Miroslav. 

Status: Available

N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE FOR TREATMENT OF CIRCADIAN RHYTHM DISEASES, DISORDERS AND DYSFUNCTIONS - PV 2019-757 (Voller) KINETIN
  1. Patent: CZ 310035. Granted: 18.4.2024. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav
  2. Published Application PCT/CZ2020/050094 under WO 2021/115502 (17.6.2021)
  3. Patent: US 12,558,358. Granted: 24.2.2026. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav
  4. Patent: EP 4072555. Granted: 22.1.2025. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav

Status: Available

Doctoral mentorship

Vítek Dominik

Study of neurodegeneration and aging on model organisms

Stav: Probíhající od 2019.

Master mentorship

Voller Jiří Ph.D.

High-throughput screenining for anti-aging and neuroprotective compounds

Stav: Ongoing od 2022.

Drozdová Barbora

Searching for neuroprotective substances using high-format screening

Stav: Absolvoval od 2024 do 2025.

Szymczyskova Beata

Isolation of tardigrades from the environment and their characterization

Stav: Absolvoval od 2024 do 2025.

Bachelor mentorship

Pertlová Markéta

Identification of genes related to cell death and cell cycle blockage in the genome of tardigrades.

Stav: Graduated od 2024 do 2025.

Volná místa

1 Molekulární a buněčná biologie
Projekt: Search and characterization of substances for the therapy of congenital or acquired diseases caused by aberrant pre-mRNA splicing
Vedoucí: Voller Jiří Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční formě studia
1 Chemická biologie a experimentální terapie
Projekt: Search and study of the mechanism of action of substances affecting the viability and motility of human spermatozoa
Vedoucí: Voller Jiří Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční formě studia
2 Molekulární a translační medicína
Projekt: Physiology and pathophysiology of aging
Vedoucí: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 místa v prezenční formě studia
Projekt: Search and study of the mechanism of action of new modulators of circadian rhythms for the therapy of civilization diseases
Vedoucí: Voller Jiří Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 místo v prezenční formě studia