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Academic title: Professor
Phone: 776391255
Groups: IMTM, LEM, STAFF

About me

I was initially formed in Biochemistry (Temple University), and then I did doctoral studies in physiological sciences, specialising in Biochemistry, Metabolism and immunology. I was a professor for more than 30 years at the Faculty of Medicine and the Institute of Immunology of the Faculty of Medicine of Universidad Central de Venezuela. My big area of expertise is inflammation, with ample background in immune response, cell metabolism, lipidomic, signal transduction and pharmacology. Currently, I am involved in a project on Cancer and immune response and others in Covid and long Covid (pending funding).

 

Journals

GARCIA, A., J. DE SANCTIS
Vaccine Adjuvants and Delivery Systems: A Comprehensive Review. International Journal of Molecular Sciences. 2026, 27(10), 4271, ISSN: 1422-0067, PMID: 42196252,  PDF.
FERNANDEZ-MESTRE, M., E. SALAZAR-ALCALA, J. DE SANCTIS, D. MORENO, J. GARMENDIA, O. REGALADO-GUTIERREZ, M. PENA
Prevalence of GSTM1 and GSTT1 null polymorphisms in an admixed healthy Venezuelan population: implications for pharmacogenetic baselines. Frontiers in Genetics. 2026, 17, 1792974, ISSN: 1664-8021, PMID: 42100347,  PDF.
SUAREZ, A., K. CHAVEZ, J. GARMENDIA, C. DE SANTCTIS, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, J. DE SANCTIS
New Derivatives of Caracasine Acid with Anti-Leukemic Activity and Limited Effectiveness in Spheroid Cultures. Pharmaceuticals . 2025, 18(7), 1043, ISSN: 1424-8247, PMID: 40732330,  PDF.

Books & book chapters

Pharmacologic Modulation of the Immune Response Against Tumours in the Elderly, 1.vyd, Singapore, Springer Verlag, 2020, 8, 157-164, ISBN: 978-981-15-7585-3,

Bachelor mentorship

Kovačíková Lucia

PDL-1 expression in stimulated lymphocytes

Status: Ongoing from 2025.

Khuat Michal

Role of CuEt, GSK3, and Syk inhibitors on survivin protein in leukemia cell lines

Status: Ongoing from 2026.

Smrčková Nela

Role of CuEt, GSK3, and Syk inhibitors on survivin protein in colon carcinoma cell lines

Status: Ongoing from 2026.

Open positions

2 Molecular and Translational Medicine
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Role of PD1 signaling in the immune response against solid tumors
Supervisors: De Sanctis Juan Bautista Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 1 position (full-time), 1 position (part-time)