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Academic title: Ing.
Phone: +420 585632186
Groups: IMTM, LEM, POSTDOCTORAL FELLOW, STAFF

Postdoctoral training

Status: Ongoing.

About me

I am a research scientist passionate for molecular and cellular biology, masive parallel sequencing and gene-expresion analysis. I always enjoy datamining of biologicaly relevant data and the comparison of data with already known information. I was involved in different studies such as wound healing characterization, experimental diabetes mellitus, effect of potentially active compounds or radiation on cells in vitro. I was responsible for a developement of a small laboratory for studing microbial biofilm in vitro. With my collegues, we are working on the developement of NGS methods for predicive diagnostics of cancer and methylome profiling. Recently we successfully released fastGEN NGS technology products together with our industrial partners. Currently we are also studying how the somatic mutations in blood cells that are appearing during aging and are connected to different vascular pathologic processeses. 

Journals

KALITA, O., Z. ŠPORIKOVÁ, M. HAJDÚCH, M. HOUDOVÁ MEGOVÁ, R. SLAVKOVSKÝ, L. HRABALEK, M. HALAJ, Y. KLEMENTOVÁ, M. DOLEZAL, J. DRÁBEK, L. TUCKOVA, J. EHRMANN, J. VRBKOVÁ, R. TROJANEC, M. VAVERKA
The Influence of Gene Aberrations on Survival in Resected IDH Wildtype Glioblastoma Patients: A Single-Institution Study. Current Oncology. 2021, 28(2), 1280-1293, ISSN: 1198-0052, PMID: 33801093,  PDF.
Pitfalls of commercially available HPV tests in HPV68a detection. PLOS One. 2019, 14(8), e0220373, ISSN: 1932-6203, PMID: 31381580,  PDF.
The absence of high-risk human papillomavirus in Czech non-small cell lung cancer cases. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2020, 164(1), 71-76, ISSN: 1213-8118, PMID: 30631209,

Master mentorship

Kalousová Barbora M.Sc.

Optimization of somatic mutation diagnostics in selected tumors with help of massive parallel sequencing

Status: Graduated from 2017 to 2019.

Kotková Lucie

Optimization of library technology for multi-parallel sequencing in the colorectal cancer diagnostics

Status: Graduated from 2015 to 2017.

Svatošová Barbora

Development of new diagnostic solutions for the detection of somatic mutations in brain tumours

Status: Graduated from 2023 to 2025.

Open positions

1 Biomarkers: Identification and validation
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
1 Molecular and Translational Medicine
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training