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Koberna Karel CSc.

Journals

A new technique for the analysis of metabolic pathways of cytidine analogues and cytidine deaminase activities in cells. Scientific Reports. 2023, 13(1), 20530, ISSN: 2045-2322 , PMID: 37993628,
Basic Methods of Cell Cycle Analysis. International Journal of Molecular Sciences. 2023, 24(12), 3674, ISSN: 1422-0067, PMID: 36835083,  PDF.
HODOŇ, J., I. FRYDRYCH, Z. TRHLÍKOVÁ, J. POKORNÝ, L. BORKOVÁ, S. BENICKÁ, M. VLK, B. LIŠKOVÁ, A. KUBÍČKOVÁ, M. MEDVEDÍKOVÁ, M. PISÁR, J. ŠAREK, V. DAS, A. LIGASOVÁ, K. KOBERNA, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs. European Journal of Medicinal Chemistry. 2022, 243, 114777, ISSN: 0223-5234, PMID: 36174412,  PDF.

Books & book chapters

In situ detection of overall and replicated mitochondrial DNA in mammalian cells , 1.vyd., Olomouc, Palacky University, 2021, 18, 129-140, Dedication: LO1304, ISBN: 978-80-244-6049-9,
In situ detection of replicated DNA in mammalian cell nuclei , 1.vyd., Olomouc, Palacky University, 2021, 17, 119-128, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Laboratory Techniques in Cellular and Molecular Medicine, 1.vyd., Olomouc, Palacky University, 2021, 436 s, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Intellectual property

SENSOR FOR DETERMINING THE ACTIVITY OF URACIL GLYCOSYLASE DNA IN SOLUTIONS AND A SET CONTAINING IT (Koberna)

Utility Model: CZ 34442. Granted: 6.10.2020. Ownership: Palacký University Olomouc. Inventors: Koberna KarelLigasová Anna.

Status: Available

SENSOR FOR DETERMINING NUCLEASE ACTIVITY IN SOLUTIONS AND A KIT CONTAINING IT (Koberna)

Utility Model CZ 34386. Granted: 15.9.2020. Ownership: Palacký University Olomouc. Inventors: Karel Koberna, Anna Ligasová.

Status: Available

DEVICE FOR FACILITATING THE HANDLING OF SOLVENTS, MIXTURES AND SAMPLES ON CARRIERS, SET FOR HANDLING THEM, AND USE THEREOF "CytoTrap" (Koberna)
  1. Patent: CZ 307454. Granted: 5.9.2018. Ownership: Palacký University Olomouc. Inventors: KOBERNA KarelLIGASOVÁ Anna
  2. Published Application PCT/CZ2017/050065 under WO 2018/113804 (28.6.2018)
  3. Patent: EP 3558526. Granted: 20.9.2023. Ownership: Palacký University Olomouc. Inventors: KOBERNA KarelLIGASOVÁ Anna

Status: Terminated

Master mentorship

Zálešáková Zuzana

Testing and optimization of new non-destructive method for determining the activity of cytidine deaminase for use of various cell lines

Stav: Absolvoval od 2015 do 2017.

Bachelor mentorship

Moštěk Jan

Base excision repairs

Stav: Absolvoval od 2017 do 2021.
Pasecká Martina

Optimization of the method for determining the activity of uracil glycosylase and its application to compare the activity of uracil glycosylase in different cell lines

Kociánová Markéta

Metabolic pathways of deoxycytidine and their impact on the cancer treatment by deoxycytidine analog

Stav: Probíhající od 2023.