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Phone: +420 585634873
Groups: IMTM, LIG, STAFF

About me

Specializing in cellular stresses and their link to cancer development and treatment. Another specialization includes advanced microscopic techniques (the head of the bioimaging core facility: https://imtm.cz/core-facilities/bioimaging-core-facility ). Actively participated in the research of more than 10 national and international projects. Published more than >40 original investigations and three patents, >3000 citations, H-index 24

Journals

KOVACICOVA, K., M. SKOLNAJA, M. HEINMAA, M. MISTRÍK, P. PATA, I. PATA, J. BÁRTEK, M. VINCIGUERRA
Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer. Frontiers in Oncology. 2018, 8, 459, ISSN: 2234-943X, PMID: 30425964,  PDF.
ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES, J. BÁRTEK
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199, ISSN: 0028-0836, PMID: 29211715,
TURI, Z., M. ŠENKYŘÍKOVÁ, M. MISTRÍK, J. BÁRTEK, P. MOUDRÝ
Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells. Cell Cycle. 2017, 17(1), 92-101, ISSN: 1538-4101, PMID: 29143558,

Open positions

1 Molecular and cellular biology
Project: DNA damage signaling in the cellular response to stress
Supervisors: Mistrík Martin Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
2 Molecular and Translational Medicine
Project: Cellular stress in health and disease
Supervisors: Mistrík Martin Ph.D., Moudrý Pavel Ph.D., Škrott Zdeněk Ph.D.
Available: 3
Intended for: Doctoral training
Project: Identification of cellular stress pathways essential for cancer cell survival
Supervisors: Mistrík Martin Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position