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Academic title: M.Sc.
Phone: +420 585 632 144
Groups: DOCTORAL STUDENT, IMTM, LIG, STAFF

Doctoral training

Cellular stress in health and disease

Specialization: Molecular and Translational Medicine
Status: Ongoing from 2023.

About me

Doctoral student, member of the LIG (Laboratory of Genome Integrity) research group under the supervision of Mgr. Martin Mistrík, PhD. Received a Master's degree in Molecular and Cell Biology at the Palacky University Olomouc.

Research interests: cancer cell biology, molecular mechanisms, identification of new therapeutic targets in cancer

Journals

Autophagy revealed as a targetable vulnerability in senescent cells by cell painting phenotypic profiling: a mechanistic study of MCOPPB and related compounds. Geroscience. 2026, ISSN: 2509-2723, PMID: 42062708,  PDF.
LÖFFELMANN, M., Z. ŠKROTT, D. MAJERA, P. STARHA, V. KRYŠTOF, M. MISTRÍK
Identification of novel dithiocarbamate-copper complexes targeting p97/NPL4 pathway in cancer cells. European Journal of Medicinal Chemistry. 2023, 261, 115790, ISSN: 0223-5234 , PMID: 37690264,

Master mentorship

Uhrinová Daniela

Mechanisms of cuproptotic cell death induced by copper ionophores

Status: Graduated from 2024 to 2026.

Bachelor mentorship

Martínek Jan

Proteotoxic stress in cancer cells induced by copper ionophores

Status: Graduated from 2023 to 2025.